Sports & Wellness

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Traits / Category collection

Sports & Wellness

Review the available associations, their supporting evidence and the limits of each result.

Selected sample
Demo Report
In this collection
14 traits
Access
Full report
Associations need context

These reports are for educational and informational purposes. They do not constitute medical advice or diagnosis. Consult healthcare professionals for medical decisions.

Genetics, environment and experience can all influence a trait. A statistical association is not a fixed outcome or a definition of a person.

About this category

Sports & Wellness blend physical activity with holistic health practices to enhance fitness, prevent disease, and boost mental wellbeing.

Environmental Factors: Together, these elements create a sustainable lifestyle: setting goals, tracking progress, and embracing active rest and self‑care reinforce habits that foster long‑term health, resilience, and vitality..

Core Function: Regular exercise stimulates endorphin release, reducing stress, improving mood, and sharpening cognitive function.

Wellness extends beyond exercise to encompass nutrition, stress management, sleep, and social connection.

Health Impact: Sports & Wellness blend physical activity with holistic health practices to enhance fitness, prevent disease, and boost mental wellbeing.

Review your results

Available trait reports

14 traits in this collection.

Ankle injuries (sprains and ligament damage) are among the most common musculoskeletal injuries in sport. GWAS work has identified variants near collagen and elastin genes (such as COL1A1 and COL5A1) linked to…

Genetic tendency

Average genetic tendency

Markers
31
Studies
1
Evidence rating
Very Low

Kim SK 09/28/2017

Caffeine is one of the most studied ergogenic aids in sport. Some people respond strongly to a given dose while others gain little benefit or feel side effects. Variants in CYP1A2 (caffeine metabolism) and…

Genetic tendency

Faster caffeine metabolism in smokers and heavy coffee consumers

Markers
1
Studies
1
Evidence rating
Very high

60% genetic influence 40% environmental influence

Goldstein ER 01/27/2010

Sports & Wellness

Exercise response

Exercise response covers how cardiorespiratory fitness, strength, and metabolic health change with the same training stimulus across different people. GWAS and candidate-gene work has identified variants…

Genetic tendency

Slightly increased benefits from daily exercise

Markers
1
Studies
1
Evidence rating
Very high

60% genetic influence 40% environmental influence

Stefan N 2007 May

After eccentric or unaccustomed exercise, muscle fibers experience small-scale damage. Regenerative capacity describes how quickly the muscle rebuilds. GWAS and candidate-gene work has identified variants in…

Insufficient data

The markers available in this file do not support a result for this trait.

Markers
0
Studies
0
Evidence rating
Inconclusive, missing DNA markers

60% genetic influence 40% environmental influence

The second phase of exercise-induced muscle damage covers the days following the initial injury, when inflammation, soreness, and repair processes overlap. Variants in inflammation, muscle structure, and…

Genetic tendency

Less odds of increased exercise-induced muscle damage

Markers
1
Studies
1
Evidence rating
Very high

60% genetic influence 40% environmental influence

Dennis RA 11/01/2004

Ligament injuries (especially in knees, ankles, and shoulders) are common in sport and active life. Some people seem to have more "loose" or injury-prone connective tissue. GWAS and candidate-gene work has…

Insufficient data

The markers available in this file do not support a result for this trait.

Markers
0
Studies
0
Evidence rating
Inconclusive, missing DNA markers

60% genetic influence 40% environmental influence

Lumbar disc disease covers degeneration and herniation of intervertebral discs in the lower back, a common cause of back pain. GWAS work has identified variants near collagen, growth factor, and disc-matrix…

Genetic tendency

Increased tendency of intervertebral disc degeneration

Markers
1
Studies
2
Evidence rating
Very high

60% genetic influence 40% environmental influence

Wang W 10/15/2016

Moderate to vigorous physical activity (MVPA) is one of the most studied health behaviors, often measured by self-report or accelerometers. GWAS work has identified variants linked to physical activity levels,…

Genetic tendency

Lower moderate physical activity tendency

Markers
12
Studies
1
Evidence rating
Very Low

Klimentidis YC 2018 Jun

Sports & Wellness

Muscle strength

Muscle strength research looks at maximal force a muscle or muscle group can produce. It is partly heritable and an important predictor of healthy aging. GWAS work has identified variants linked to grip…

Insufficient data

The markers available in this file do not support a result for this trait.

Markers
0
Studies
0
Evidence rating
Inconclusive, missing DNA markers

60% genetic influence 40% environmental influence

Sports & Wellness

Muscle volume

Muscle volume refers to total skeletal muscle mass and is studied because it influences strength, metabolism, and resilience to illness. GWAS work has identified variants linked to lean mass and muscle size,…

Genetic tendency

Average muscle volume

Markers
1
Studies
1
Evidence rating
Very high

60% genetic influence 40% environmental influence

Pistilli EE 2008 Jul

Sports & Wellness

Muscular endurance

Muscular endurance refers to a muscle's ability to sustain repeated contractions before fatiguing. It depends partly on muscle fiber composition and aerobic capacity. GWAS and candidate-gene work has…

Genetic tendency

Slightly increased performance in endurance sports

Markers
1
Studies
4
Evidence rating
Very high

60% genetic influence 40% environmental influence

Tsianos GI 2010 Mar

Sports & Wellness

Muscular power

Muscular power is the ability to produce force quickly, important for sprinting, jumping, and explosive sport movements. A common variant in ACTN3 (the R577X variant) has been linked to muscle fiber…

Genetic tendency

Good performance in endurance and power sports

Markers
1
Studies
4
Evidence rating
Very high

60% genetic influence 40% environmental influence

Ben-Zaken S 2019 Jun

Lower-extremity tendinopathies include patellar, Achilles, and other leg tendon overuse injuries, common in runners and jumpers. GWAS and candidate-gene work has identified variants near collagen and matrix…

Genetic tendency

Slightly higher tendency of tendinopathies in lower extremities (legs)

Markers
1
Studies
1
Evidence rating
Very high

60% genetic influence 40% environmental influence

Raleigh SM 2009 Jul

Upper-extremity tendinopathies affect tendons in the shoulder, elbow (such as tennis or golfer's elbow), and wrist, often from repetitive use. Variants in collagen and matrix genes have been linked to…

Insufficient data

The markers available in this file do not support a result for this trait.

Markers
0
Studies
0
Evidence rating
Inconclusive, missing DNA markers

60% genetic influence 40% environmental influence

Read the report, then the evidence.

Marker coverage
Available results depend on the markers detected in your DNA file. Missing data can prevent a supported result.
Strength of evidence
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