Genome-wide association study of a quantitative disordered gambling trait
Authors: Lind PA, Zhu G, Montgomery GW, Madden PA, Heath AC, Martin NG, Slutske WS
Study sample: 1,312 individuals (european ancestry)
Traits - Genetic associations studied in gambling-behavior research
Download PDF creates a visual, rasterized copy. Use Print for selectable text and better assistive-technology support.
Gambling behavior research studies inherited differences in problem gambling vulnerability.
GWAS and candidate-gene work has identified variants in dopamine and reward pathway genes linked to gambling traits.
This result reflects research-level variation in reward biology and is not a diagnosis of gambling disorder.
Access, social context, mental health, life events, and exposure to gambling all strongly affect actual gambling behavior.
Research summary, not an individual result
This trait is presented as population-level genetic research rather than an individual Low/High verdict, because the science behind it is either too preliminary, too easily misread as a diagnosis, or too sensitive to responsibly reduce to a single badge.
Was this explanation clear and useful?
Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs11060736 | TC | C | 94.10% | |
| rs10812227 | -- | 86.80% | ||
| rs12237653 | -- | C | 86.80% | |
| rs8064100 | -- | 58.20% | ||
| rs9383153 | -- | 94.80% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
2013 May Addict Biol
Authors: Lind PA, Zhu G, Montgomery GW, Madden PA, Heath AC, Martin NG, Slutske WS
Study sample: 1,312 individuals (european ancestry)
Your purchase is ready. Reloading the page to unlock your content...
Check your email for a secure link to access your account and this purchase.