Traits - Mosquito bite itch susceptibility
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Itch intensity after a mosquito bite varies widely between people because of differences in immune response to mosquito saliva.
GWAS work has identified variants near immune and skin biology genes linked to itch intensity.
This result reflects research-level variation in skin and immune biology and is not a clinical evaluation.
Mosquito species, prior exposure, body location, scratching, and use of antihistamines all affect how strongly bites itch.
Lower mosquito bite itch susceptibility tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs778798 | CC | C | 74.00% | |
| rs971891 | CT | T | 9.54% | |
| rs2282718 | GA | 60.50% | ||
| rs2516703 | GG | G | 39.76% | |
| rs3094092 | CC | C | 96.73% | |
| rs3104376 | CC | 23.66% | ||
| rs3117191 | CC | C | 72.36% | |
| rs4706020 | AA | 88.44% | ||
| rs521977 | GG | 14.92% | ||
| rs72809593 | TG | 98.98% | ||
| rs5875313 | -- | 0.00% | ||
| rs59383773 | -- | 0.00% | ||
| rs61863408 | -- | T | 3.71% | |
| rs61864810 | -- | A | 51.50% | |
| rs67539049 | -- | A | 9.17% | |
| rs73195822 | -- | 91.05% | ||
| rs7487075 | -- | A | 55.41% | |
| rs75583553 | -- | 51.68% | ||
| rs7701967 | -- | A | 10.62% | |
| rs77133669 | -- | C | 2.40% | |
| rs7923452 | -- | 78.99% | ||
| rs79712192 | -- | T | 3.93% | |
| rs9281557 | -- | 0.00% | ||
| rs9541009 | -- | T | 1.14% | |
| rs10117812 | -- | G | 66.57% | |
| rs10261971 | -- | G | 53.90% | |
| rs1055559 | -- | T | 97.94% | |
| rs10876947 | -- | T | 64.46% | |
| rs11242103 | -- | G | 0.00% | |
| rs1127348 | -- | C | 12.18% | |
| rs113264677 | -- | C | 10.26% | |
| rs11555872 | -- | T | 36.26% | |
| rs11746729 | -- | A | 22.08% | |
| rs11751172 | -- | T | 24.40% | |
| rs11954099 | -- | 67.25% | ||
| rs12050947 | -- | 84.17% | ||
| rs12532214 | -- | 81.81% | ||
| rs12832728 | -- | 45.30% | ||
| rs12907526 | -- | G | 90.99% | |
| rs12949918 | -- | 58.80% | ||
| rs13129280 | -- | T | 42.47% | |
| rs139161943 | -- | C | 0.36% | |
| rs139735807 | -- | 87.64% | ||
| rs139746351 | -- | 88.50% | ||
| rs143211693 | -- | 93.51% | ||
| rs149082847 | -- | G | 8.50% | |
| rs150582667 | -- | T | 0.30% | |
| rs1548306 | -- | T | 63.40% | |
| rs16931910 | -- | C | 11.98% | |
| rs1784581 | -- | C | 37.58% | |
| rs183132916 | -- | A | 0.10% | |
| rs190369032 | -- | 97.06% | ||
| rs1985157 | -- | 59.96% | ||
| rs199834894 | -- | 0.00% | ||
| rs2085423 | -- | G | 74.20% | |
| rs2092850 | -- | A | 28.93% | |
| rs2248116 | -- | 41.40% | ||
| rs2857598 | -- | C | 95.81% | |
| rs2967678 | -- | T | 14.70% | |
| rs309392 | -- | T | 60.90% | |
| rs3130040 | -- | 3.16% | ||
| rs324014 | -- | 56.60% | ||
| rs34034104 | -- | A | 14.82% | |
| rs34119525 | -- | 94.45% | ||
| rs34180132 | -- | 67.31% | ||
| rs35260072 | -- | C | 13.46% | |
| rs35403253 | -- | T | 11.90% | |
| rs35488337 | -- | A | 76.20% | |
| rs3752962 | -- | C | 23.00% | |
| rs4959021 | -- | 14.42% | ||
| rs55975060 | -- | C | 10.22% | |
| rs5750339 | -- | 45.70% | ||
| rs80016369 | -- | 99.52% | ||
| rs9276434 | -- | T | 94.21% | |
| rs1099448 | -- | T | 57.47% | |
| rs11205006 | -- | T | 73.52% | |
| rs11265461 | -- | 64.40% | ||
| rs112990264 | -- | 98.00% | ||
| rs12122629 | -- | C | 1.32% | |
| rs12123821 | -- | T | 5.30% | |
| rs12125543 | -- | G | 34.80% | |
| rs12133641 | -- | G | 39.50% | |
| rs13079741 | -- | 54.20% | ||
| rs141623444 | -- | G | 1.14% | |
| rs2373226 | -- | T | 26.42% | |
| rs3111414 | -- | G | 77.80% | |
| rs6673928 | -- | T | 25.50% | |
| rs6809854 | -- | G | 19.70% | |
| rs72811546 | -- | T | 0.86% | |
| rs72816448 | -- | 97.70% | ||
| rs72992640 | -- | T | 21.39% | |
| rs74664319 | -- | 98.32% | ||
| rs75697854 | -- | C | 0.78% | |
| rs7614601 | -- | 64.46% | ||
| rs7625328 | -- | 47.90% | ||
| rs7639513 | -- | T | 29.41% | |
| rs7644634 | -- | T | 42.81% | |
| rs78037977 | -- | G | 12.30% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Jones AV, Tilley M, Gutteridge A, Hyde C, Nagle M, Ziemek D, Gorman D, Fauman EB, Chen X, Miller MR, Tian C, Hu Y, Hinds DA, Cox P, Scollen S
Study sample: 84,724 individuals (european ancestry)
