Traits - Left-handedness

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Left-handedness

Behavioral Patterns

Handedness reflects which hand is preferred for fine motor tasks. About 10 percent of people are predominantly left-handed.

GWAS work has identified variants linked to left-handedness, including signals near genes involved in microtubule biology and brain development.

This result reflects research-level variation in handedness biology and is not direct observation of hand preference.

Cultural pressures, training, brain injury, and developmental factors also affect the hand actually used for various tasks.

Selected sample
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Report markers
41 SNP entries
Genes
0
Research
1 study
Your report

Genetic tendency

Average genetic tendency

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Explore the evidence

Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs11820337CTT34.86%
rs1424114CTT35.30%
rs3132584GTT20.56%
rs9645660TC52.07%
rs35551703--A3.76%
rs4550447--C12.04%
rs45527431--91.48%
rs4676276--A51.62%
rs4822384--39.11%
rs4953572--A66.15%
rs55974014--A21.42%
rs5762532--58.99%
rs62036618--C61.27%
rs62213410--71.07%
rs6224--T46.72%
rs62251113--A36.65%
rs66479618--T19.97%
rs66513715--20.10%
rs7132513--60.56%
rs8012503--G87.55%
rs8016028--T81.07%
rs806188--31.81%
rs1000565--G60.17%
rs10081960--G60.10%
rs11168884--T34.30%
rs11227478--A20.93%
rs112737242--35.07%
rs12414988--A20.86%
rs13006483--T28.48%
rs13107325--T7.88%
rs1398651--A56.33%
rs1422070--A59.54%
rs148342778--64.82%
rs1526194--57.89%
rs201072423--50.80%
rs2194028--T33.87%
rs2233324--16.18%
rs246628--40.70%
rs28658282--T10.26%
rs34550543--T40.63%
rs9581731--C70.76%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

2021 Jan Nat Hum Behav

Authors: Cuellar-Partida G, Tung JY, Eriksson N, Albrecht E, Aliev F, Andreassen OA, Barroso I, Beckmann JS, Boks MP, Boomsma DI, Boyd HA, Breteler MMB, Campbell H, Chasman DI, Cherkas LF, Davies G, de Geus EJC, Deary IJ, Deloukas P, Dick DM, Duffy DL, Eriksson JG, Esko T, Feenstra B, Geller F, Gieger C, Giegling I, Gordon SD, Han J, Hansen TF, Hartmann AM, Hayward C, Heikkilä K, Hicks AA, Hirschhorn JN, Hottenga JJ, Huffman JE, Hwang LD, Ikram MA, Kaprio J, Kemp JP, Khaw KT, Klopp N, Konte B, Kutalik Z, Lahti J, Li X, Loos RJF, Luciano M, Magnusson SH, Mangino M, Marques-Vidal P, Martin NG, McArdle WL, McCarthy MI, Medina-Gomez C, Melbye M, Melville SA, Metspalu A, Milani L, Mooser V, Nelis M, Nyholt DR, O&#39, Connell KS, Ophoff RA, Palmer C, Palotie A, Palviainen T, Pare G, Paternoster L, Peltonen L, Penninx BWJH, Polasek O, Pramstaller PP, Prokopenko I, Raikkonen K, Ripatti S, Rivadeneira F, Rudan I, Rujescu D, Smit JH, Smith GD, Smoller JW, Soranzo N, Spector TD, Pourcain BS, Starr JM, Stefánsson H, Steinberg S, Teder-Laving M, Thorleifsson G, Stefánsson K, Timpson NJ, Uitterlinden AG, van Duijn CM, van Rooij FJA, Vink JM, Vollenweider P, Vuoksimaa E, Waeber G, Wareham NJ, Warrington N, Waterworth D, Werge T, Wichmann HE, Widen E, Willemsen G, Wright AF, Wright MJ, Xu M, Zhao JH, Kraft P, Hinds DA, Lindgren CM, Mägi R, Neale BM, Evans DM, Medland SE

Study sample: 190,460 individuals (european ancestry)

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Coverage: 4/41 SNP entries detected (9%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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