A genome-wide association study of bitter and sweet beverage consumption
Authors: Zhong VW, Kuang A, Danning RD, Kraft P, van Dam RM, Chasman DI, Cornelis MC
Study sample: 39,924 individuals (european ancestry)
Traits - Bitter alcoholic beverage consumption tendency
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This research area looks at how often people consume bitter alcoholic drinks like beer, dry wine, or spirits with bitter notes.
GWAS work has identified variants near taste receptor and alcohol-metabolism genes that influence preference for bitter alcoholic beverages.
This result reflects research-level variation in beverage preference and is not a recommendation about alcohol intake.
Cuisine, social context, age of first exposure, overall taste sensitivity, and other lifestyle factors strongly shape real consumption.
Average genetic tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs196376 | GG | G | 57.68% | |
| rs2585807 | CC | C | 83.10% | |
| rs34060476 | AG | G | 13.35% | |
| rs3803800 | AG | G | 78.88% | |
| rs4726481 | GT | T | 60.10% | |
| rs4787717 | AA | A | 83.65% | |
| rs4815364 | AA | A | 60.80% | |
| rs531071 | AG | G | 53.79% | |
| rs7307912 | CT | 76.77% | ||
| rs7845740 | GG | 35.00% | ||
| rs802196 | CT | T | 32.57% | |
| rs928736 | TT | 30.64% | ||
| rs9299083 | TC | C | 23.80% | |
| rs10506274 | GT | 51.21% | ||
| rs10892761 | CC | C | 42.70% | |
| rs11940694 | GG | G | 60.23% | |
| rs1229984 | CC | C | 97.25% | |
| rs13242133 | AA | A | 20.51% | |
| rs1891196 | -- | G | 43.60% | |
| rs1981309 | -- | G | 25.21% | |
| rs2018910 | -- | T | 17.97% | |
| rs2274794 | -- | 67.23% | ||
| rs2348072 | -- | 28.27% | ||
| rs2418959 | -- | T | 53.59% | |
| rs2494169 | -- | T | 32.01% | |
| rs2622167 | -- | A | 42.67% | |
| rs28525613 | -- | A | 84.82% | |
| rs17520061 | -- | G | 85.84% | |
| rs28616142 | -- | T | 39.50% | |
| rs28929474 | -- | 97.98% | ||
| rs324012 | -- | T | 44.88% | |
| rs35326581 | -- | C | 74.25% | |
| rs35572189 | -- | A | 36.15% | |
| rs36053727 | -- | G | 56.82% | |
| rs4279114 | -- | G | 24.71% | |
| rs4426365 | -- | A | 36.78% | |
| rs503397 | -- | T | 28.22% | |
| rs606151 | -- | A | 68.89% | |
| rs6136459 | -- | 59.97% | ||
| rs61523335 | -- | 85.43% | ||
| rs61873510 | -- | 66.87% | ||
| rs61884414 | -- | G | 9.48% | |
| rs62135521 | -- | 95.13% | ||
| rs62305780 | -- | G | 10.25% | |
| rs6855649 | -- | G | 36.08% | |
| rs72768626 | -- | G | 94.20% | |
| rs7407346 | -- | 17.89% | ||
| rs74424378 | -- | 76.21% | ||
| rs74790649 | -- | A | 98.23% | |
| rs756747 | -- | G | 52.22% | |
| rs7680631 | -- | T | 69.98% | |
| rs77509885 | -- | G | 5.21% | |
| rs780569 | -- | 28.95% | ||
| rs78119163 | -- | G | 88.38% | |
| rs78423589 | -- | A | 97.38% | |
| rs78631521 | -- | A | 3.45% | |
| rs78876991 | -- | C | 93.53% | |
| rs79059649 | -- | A | 94.64% | |
| rs7935528 | -- | A | 45.07% | |
| rs8016984 | -- | 49.42% | ||
| rs9607812 | -- | A | 81.13% | |
| rs965628 | -- | C | 58.63% | |
| rs973894 | -- | G | 27.94% | |
| rs9809760 | -- | C | 45.36% | |
| rs9826135 | -- | T | 23.06% | |
| rs1004787 | -- | A | 53.28% | |
| rs10894762 | -- | 77.23% | ||
| rs11030084 | -- | 81.32% | ||
| rs1104608 | -- | 57.39% | ||
| rs111519289 | -- | A | 5.35% | |
| rs111712190 | -- | T | 95.64% | |
| rs113443718 | -- | 69.13% | ||
| rs1153628 | -- | C | 14.60% | |
| rs11648570 | -- | C | 10.74% | |
| rs11692435 | -- | A | 8.40% | |
| rs11754010 | -- | 62.59% | ||
| rs11773627 | -- | C | 19.71% | |
| rs117920416 | -- | A | 2.40% | |
| rs11864886 | -- | G | 22.67% | |
| rs11993084 | -- | 77.27% | ||
| rs12544687 | -- | T | 45.11% | |
| rs1260326 | -- | C | 60.34% | |
| rs12943365 | -- | G | 61.09% | |
| rs12945870 | -- | T | 56.83% | |
| rs13135092 | -- | G | 91.76% | |
| rs1315005 | -- | G | 30.21% | |
| rs13157159 | -- | 20.78% | ||
| rs13390019 | -- | C | 86.70% | |
| rs13413953 | -- | G | 63.96% | |
| rs139910 | -- | G | 24.97% | |
| rs145898511 | -- | G | 97.36% | |
| rs16869103 | -- | A | 80.65% | |
| rs17028973 | -- | 81.18% | ||
| rs1724409 | -- | T | 74.15% | |
| rs17747739 | -- | T | 6.23% | |
| rs1788025 | -- | 59.74% | ||
| rs1788820 | -- | G | 65.48% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Zhong VW, Kuang A, Danning RD, Kraft P, van Dam RM, Chasman DI, Cornelis MC
Study sample: 39,924 individuals (european ancestry)