A genome-wide association study of bitter and sweet beverage consumption
Authors: Zhong VW, Kuang A, Danning RD, Kraft P, van Dam RM, Chasman DI, Cornelis MC
Study sample: 39,924 individuals (european ancestry)
Traits - Bitter beverage consumption tendency
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This research area looks at preference for bitter beverages such as coffee, tea, dark chocolate drinks, and tonic water.
Variants in bitter taste receptor genes (such as TAS2R38) influence sensitivity to bitter compounds and can shape beverage preference.
This result reflects research-level variation in taste biology and is not a recommended intake.
Cuisine, age, exposure history, and other taste preferences also strongly shape what bitter beverages people enjoy.
Higher bitter beverage consumption tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs1481012 | AG | G | 88.69% | |
| rs2216076 | CA | A | 12.19% | |
| rs2472297 | CT | T | 26.09% | |
| rs4410790 | CC | C | 62.98% | |
| rs738814 | GA | A | 56.60% | |
| rs10942512 | -- | 29.31% | ||
| rs1260326 | -- | C | 60.58% | |
| rs1393320 | -- | T | 45.15% | |
| rs17685 | -- | A | 27.85% | |
| rs1808056 | -- | A | 46.16% | |
| rs56113850 | -- | C | 57.66% | |
| rs5758274 | -- | G | 66.74% | |
| rs7693253 | -- | 44.26% | ||
| rs10201194 | -- | 31.19% | ||
| rs10915573 | -- | G | 24.99% | |
| rs10973268 | -- | 45.59% | ||
| rs112401219 | -- | A | 97.34% | |
| rs11247124 | -- | A | 23.73% | |
| rs115821138 | -- | A | 3.16% | |
| rs12787646 | -- | 65.48% | ||
| rs13400680 | -- | G | 73.73% | |
| rs138828109 | -- | T | 3.18% | |
| rs148372345 | -- | 98.14% | ||
| rs2268759 | -- | A | 59.75% | |
| rs4323895 | -- | 93.88% | ||
| rs500126 | -- | A | 41.78% | |
| rs62261464 | -- | A | 3.41% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Zhong VW, Kuang A, Danning RD, Kraft P, van Dam RM, Chasman DI, Cornelis MC
Study sample: 39,924 individuals (european ancestry)