Body Composition

Genetic associations studied in childhood blood-glucose regulation

This research area looks at how blood glucose regulation differs in children with higher body weight, who as a group are more likely to develop insulin resistance and type 2 diabetes earlier in life.

GWAS work has linked common variants to how childhood adiposity, insulin sensitivity, and glucose handling interact during growth.

This result reflects research findings in a specific pediatric population, not a personal screening for diabetes risk in any individual child.

Eating patterns, physical activity, family history, sleep, screen time, growth stage, and overall health also play a major role.

3 SNPs

1 Study

Sep 23, 2026

DEMO REPORT

Research Summary

What This Trait Studies

This section explains the population-level genetic research behind this trait. It is not an individual diagnosis or prediction.

Research summary, not an individual result

This trait is presented as population-level genetic research rather than an individual Low/High verdict, because the science behind it is either too preliminary, too easily misread as a diagnosis, or too sensitive to responsibly reduce to a single badge.

3 Genetic markers studied

3 Detected in your data

1 Gene analyzed

1 Research study

Not an individual prediction. This section summarizes population-level genetic research. It is not a personal diagnosis, a screening result, or a claim about you specifically. If this topic is a health, behavioral, or wellbeing concern for you, please talk with a qualified professional rather than relying on this genetic report.

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Scientific Evidence

Understanding the Data

SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
Genotype: Your genetic makeup at the given SNP location (e.g., CC)
Variant allele: The alternative DNA sequence at the SNP site

Variant allele frequency: Percentage of population carrying this variant
Variant found: Whether the variant was detected in your DNA file

Variant Detected

G6PC2 GeneCards

This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Genomic Location

Chr 2 Start: 168,901,223 End: 168,910,000 Build: HG19

5' end 3' end

Associated SNPs

1 / 1 detected

SNP	Genotype	Ref. Allele	Variant Allele	Frequency	Status
rs573225	A G	G	A	85.54%	Detected
Your Genotype AG Reference Allele G Variant Allele A Population Frequency 85.54% Variant Status Variant Detected Database Link NCBI dbSNP

These are the genetic markers (SNPs) analyzed for this trait. Variations detected in your genome are listed under the "Genotype" column. SNPs showing "--" were not identified in your DNA file.

SNP	Chromosome	Genotype	Variant Allele	Frequency
rs573225	2	AG	A	85.54%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Important Medical Disclaimer

This report is intended for educational and informational purposes only. It is not intended to provide medical advice or be used solely by the customer in the diagnosis, cure, mitigation, treatment, or prevention of any disease or health condition. If you have serious medical conditions, including but not limited to weight-related issues, diabetes, or heart disease, you should not make changes to your diet or exercise routine without consulting your healthcare provider. Under no circumstances should you modify your medication or medical care without professional medical guidance.

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