Traits - Histamine intolerance

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Histamine intolerance

Food Sensitivities

Histamine intolerance refers to symptoms that arise when histamine from foods or fermentation accumulates faster than the body can break it down, mainly through the enzyme DAO.

Variants in DAO and related histamine-metabolism genes have been studied as a partial explanation for why some people react more strongly to histamine-rich foods.

This result reflects research-level variation in histamine handling and is not a diagnosis of intolerance, allergy, or mast cell disease.

Diet (aged cheese, wine, fermented foods), gut health, hormones, medications, and infections also strongly affect histamine load and tolerance.

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We could not calculate your score for this genetic trait as there is not enough information in your DNA data. This may occur when specific SNPs required for analysis were not present in your uploaded file.

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Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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