Traits - Hunger response control

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Hunger response control

Body Composition

This research area looks at inherited differences in appetite regulation, satiety, and how strongly hunger signals push toward eating.

GWAS work has identified variants near hypothalamic and reward genes (including FTO and MC4R) that nudge appetite and food cue response.

This result reflects research-level variation in appetite biology and is not a measure of willpower or a prescription for portion sizes.

Sleep, stress, meal timing, food environment, hormones, medications, exercise, and protein/fiber intake also strongly shape how hungry someone feels day to day.

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Report markers
3 SNP entries
Genes
1
Research
2 studies
Your report

Genetic tendency

Average odds to be able to control hunger

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Behind this report

Review the genes, tested markers and supporting research.

Genes analyzed

Gene summaries include genomic locations and associated markers. A detected genotype does not by itself indicate a health condition.

Understanding the data
SNP
A specific genetic marker relevant to this trait.
Genotype
The DNA letters reported at a marker location.
Variant allele
The alternative DNA sequence at the SNP site.
Variant allele frequency
The reported percentage of the reference population carrying this variant.
Variant found
Whether the variant was detected in your DNA file.

1 of 1 genes have detected genotypes.

NMB

This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

GeneCards
Chromosome
15
Start
84,655,129
End
84,658,611
Build
HG19
Associated SNPs 1 / 1 detected
Associated markers for NMB
SNPGenotype Ref. alleleVariant alleleFrequencyStatus
rs1051168 GT GT13.84%Detected

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs105116815GTT13.84%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

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Coverage: 3/3 SNP entries detected (100%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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SAMPLE REPORT Example DNA profile This is a sample report with example data. It is not your personal report, and the results do not describe you.
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