Traits - Phosphorus Levels

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Phosphorus Levels

Mineral Absorption

Phosphorus is a mineral that combines with calcium in bones and teeth and is also involved in energy metabolism (as ATP) and DNA structure.

GWAS work has identified variants near genes regulating phosphorus absorption and renal handling that contribute to small differences in serum phosphorus.

This result reflects research-level variation in phosphorus biology and is not a serum phosphorus test or a recommendation about intake.

Diet, kidney function, vitamin D status, parathyroid hormone, medications, and age also strongly influence actual phosphorus levels.

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5 SNP entries
Genes
0
Research
1 study
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Genetic tendency

Average genetic tendency

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Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs1697421TTA49.00%
rs947583TCC29.00%
rs17265703--G15.00%
rs2970818--A9.00%
rs9469578--T8.00%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

2010 Jul J Am Soc Nephrol

Authors: Kestenbaum B, Glazer NL, Köttgen A, Felix JF, Hwang SJ, Liu Y, Lohman K, Kritchevsky SB, Hausman DB, Petersen AK, Gieger C, Ried JS, Meitinger T, Strom TM, Wichmann HE, Campbell H, Hayward C, Rudan I, de Boer IH, Psaty BM, Rice KM, Chen YD, Li M, Arking DE, Boerwinkle E, Coresh J, Yang Q, Levy D, van Rooij FJ, Dehghan A, Rivadeneira F, Uitterlinden AG, Hofman A, van Duijn CM, Shlipak MG, Kao WH, Witteman JC, Siscovick DS, Fox CS

Study sample: 16,264 individuals (european ancestry)

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Coverage: 2/5 SNP entries detected (40%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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