Traits - Vitamin E Levels
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Vitamin E is a fat-soluble antioxidant present in nuts, seeds, and vegetable oils. The main biologically active form in humans is alpha-tocopherol.
GWAS studies have identified variants near genes that handle lipid transport and tocopherol metabolism, including CYP4F2 and SCARB1.
This result reflects research-level variation in vitamin E handling and is not a clinical test or a supplement recommendation.
Diet, fat absorption, liver health, and overall nutrition strongly affect real vitamin E status.
Average genetic tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs11057830 | GA | A | 15.00% | |
| rs2108622 | -- | T | 21.00% | |
| rs964184 | -- | C | 15.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
10/01/2011 Hum Mol Genet
Authors: Major JM, Yu K, Wheeler W, Zhang H, Cornelis MC, Wright ME, Yeager M, Snyder K, Weinstein SJ, Mondul A, Eliassen H, Purdue M, Hazra A, McCarty CA, Hendrickson S, Virtamo J, Hunter D, Chanock S, Kraft P, Albanes D
Study sample: 992 individuals (european ancestry)
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