Iron Levels

Mineral Absorption

Iron is essential for hemoglobin in red blood cells and for many enzymes. Researchers track several iron biomarkers, including transferrin, ferritin, and serum iron.

Variants in HFE and TMPRSS6, among others, have been linked to differences in iron absorption, transport, and storage.

This result reflects research-level variation in iron-related biology and is not a blood test or a recommendation for iron supplementation.

Dietary iron intake, blood loss (including menstruation), pregnancy, inflammation, GI health, and medications also strongly influence real iron status.

All traits Compare samples

Selected sample: Demo Report
Report markers: 9 SNP entries
Genes: 0
Research: 1 study

Important Medical Disclaimer

This report is intended for educational and informational purposes only. It is not intended to provide medical advice or be used solely by the customer in the diagnosis, cure, mitigation, treatment, or prevention of any disease or health condition. If you have serious medical conditions, including but not limited to weight-related issues, diabetes, or heart disease, you should not make changes to your diet or exercise routine without consulting your healthcare provider. Under no circumstances should you modify your medication or medical care without professional medical guidance. Find more information at this link

Your report

Genetic tendency

Average genetic tendency

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Explore the evidence

Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNP	Genotype	Variant allele	Frequency
rs4921915	AA	A	78.20%
rs6486121	CT	T	63.10%
rs744653	TT	T	85.40%
rs855791	AG		44.60%
rs9990333	CT	T	46.00%
rs174577	--	A	33.00%
rs1800562	--	A	6.70%
rs8177179	--	A	52.10%
rs8177240	--		66.90%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Evidence

Very strong scientific evidence

10/29/2014 Nat Commun

Authors: Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Hälldin J, Winkelmann J, Meitinger T, Thiery J, Peters A, Waldenberger M, Rendon A, Jolley J, Sambrook J, Kiemeney LA, Sweep FC, Sala CF, Schwienbacher C, Pichler I, Hui J, Demirkan A, Isaacs A, Amin N, Steri M, Waeber G, Verweij N, Powell JE, Nyholt DR, Heath AC, Madden PA, Visscher PM, Wright MJ, Montgomery GW, Martin NG, Hernandez D, Bandinelli S, van der Harst P, Uda M, Vollenweider P, Scott RA, Langenberg C, Wareham NJ, , van Duijn C, Beilby J, Pramstaller PP, Hicks AA, Ouwehand WH, Oexle K, Gieger C, Metspalu A, Camaschella C, Toniolo D, Swinkels DW, Whitfield JB

Study sample: 23,986 individuals (european ancestry)