Traits - Life satisfaction
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Life satisfaction is a global self-evaluation of one's life and is one of the most widely used well-being measures.
GWAS work has identified variants linked to life satisfaction, with overlap with happiness, personality, and mental health traits.
This result reflects research-level variation in well-being-related traits and is not a clinical assessment.
Relationships, work, finances, health, and life circumstances all strongly shape actual life satisfaction.
Higher life satisfaction tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs10818400 | GG | G | 60.57% | |
| rs11607056 | CT | T | 32.11% | |
| rs12791990 | TC | C | 14.08% | |
| rs2398144 | CA | A | 40.43% | |
| rs2978362 | CT | T | 52.16% | |
| rs4526571 | GA | A | 38.30% | |
| rs6925748 | GG | G | 42.05% | |
| rs716508 | TT | T | 68.24% | |
| rs7396827 | CC | C | 53.45% | |
| rs3134012 | CC | C | 71.92% | |
| rs3793577 | AG | G | 53.16% | |
| rs6771444 | AA | A | 50.27% | |
| rs815710 | AG | G | 40.72% | |
| rs913021 | TT | T | 64.04% | |
| rs9287989 | TC | C | 50.66% | |
| rs9546806 | CT | T | 61.12% | |
| rs10252771 | TG | G | 31.97% | |
| rs10809441 | CT | T | 44.83% | |
| rs1660237 | CT | T | 42.03% | |
| rs17041417 | GA | A | 18.07% | |
| rs1903845 | CT | T | 35.77% | |
| rs2071303 | TC | C | 34.93% | |
| rs2715147 | CT | T | 49.91% | |
| rs10774909 | -- | G | 20.31% | |
| rs10783484 | -- | T | 25.20% | |
| rs11192283 | -- | C | 23.40% | |
| rs1155156 | -- | A | 60.18% | |
| rs11693031 | -- | G | 33.09% | |
| rs12083196 | -- | C | 23.08% | |
| rs12962538 | -- | C | 18.18% | |
| rs12967831 | -- | A | 33.52% | |
| rs1371325 | -- | G | 59.70% | |
| rs1431071 | -- | T | 28.51% | |
| rs1490176 | -- | A | 71.51% | |
| rs149979 | -- | A | 22.98% | |
| rs17417046 | -- | T | 44.32% | |
| rs1829526 | -- | G | 19.80% | |
| rs2015971 | -- | T | 44.86% | |
| rs2093623 | -- | A | 48.87% | |
| rs2149351 | -- | G | 75.89% | |
| rs215816 | -- | A | 29.73% | |
| rs2514226 | -- | C | 74.69% | |
| rs261940 | -- | G | 47.29% | |
| rs263575 | -- | A | 45.20% | |
| rs28687557 | -- | A | 77.90% | |
| rs35267052 | -- | G | 10.66% | |
| rs3781627 | -- | A | 69.41% | |
| rs57713596 | -- | T | 12.84% | |
| rs59925771 | -- | T | 10.52% | |
| rs61905363 | -- | T | 3.89% | |
| rs62551639 | -- | C | 6.22% | |
| rs6776145 | -- | C | 12.08% | |
| rs6869941 | -- | T | 49.59% | |
| rs6896348 | -- | G | 51.31% | |
| rs71301807 | -- | G | 24.20% | |
| rs7170398 | -- | T | 39.98% | |
| rs7191427 | -- | T | 25.27% | |
| rs72694240 | -- | G | 16.13% | |
| rs7374731 | -- | G | 74.68% | |
| rs77214504 | -- | T | 4.54% | |
| rs918814 | -- | C | 58.56% | |
| rs9967747 | -- | C | 86.49% | |
| rs3130614 | -- | A | 11.92% | |
| rs325501 | -- | C | 57.87% | |
| rs34020413 | -- | G | 38.26% | |
| rs35368417 | -- | C | 44.04% | |
| rs3824344 | -- | T | 37.29% | |
| rs4304650 | -- | C | 80.15% | |
| rs4461738 | -- | C | 46.46% | |
| rs4581549 | -- | T | 11.72% | |
| rs4711107 | -- | C | 29.02% | |
| rs4711152 | -- | C | 45.08% | |
| rs4799464 | -- | T | 69.41% | |
| rs4914984 | -- | G | 76.95% | |
| rs584564 | -- | G | 91.17% | |
| rs6019826 | -- | T | 13.30% | |
| rs6090940 | -- | T | 32.26% | |
| rs62460794 | -- | A | 57.50% | |
| rs62620225 | -- | T | 3.96% | |
| rs66530963 | -- | G | 14.92% | |
| rs66993685 | -- | A | 23.08% | |
| rs6721577 | -- | T | 58.36% | |
| rs6769821 | -- | A | 73.86% | |
| rs68006638 | -- | A | 8.63% | |
| rs6943746 | -- | G | 38.57% | |
| rs7154329 | -- | G | 49.95% | |
| rs7232516 | -- | A | 13.21% | |
| rs7243332 | -- | G | 30.56% | |
| rs7422667 | -- | C | 56.37% | |
| rs7526171 | -- | C | 62.54% | |
| rs7606466 | -- | G | 56.99% | |
| rs7766749 | -- | C | 9.55% | |
| rs7949802 | -- | T | 42.80% | |
| rs7989827 | -- | G | 49.11% | |
| rs8084280 | -- | T | 50.84% | |
| rs8089474 | -- | A | 80.43% | |
| rs876308 | -- | A | 41.70% | |
| rs9295661 | -- | A | 92.16% | |
| rs9380010 | -- | G | 25.02% | |
| rs9393716 | -- | G | 19.79% | |
| rs9564496 | -- | A | 31.84% | |
| rs9601120 | -- | T | 18.61% | |
| rs10497655 | -- | C | 31.09% | |
| rs10737452 | -- | T | 62.52% | |
| rs10765186 | -- | T | 50.74% | |
| rs10916951 | -- | T | 39.35% | |
| rs10967509 | -- | A | 37.94% | |
| rs111871194 | -- | C | 9.90% | |
| rs112028067 | -- | A | 21.81% | |
| rs11214441 | -- | A | 39.59% | |
| rs11214596 | -- | G | 53.50% | |
| rs114595701 | -- | T | 9.25% | |
| rs1150752 | -- | C | 11.21% | |
| rs12436091 | -- | C | 76.00% | |
| rs12479300 | -- | A | 35.83% | |
| rs12587457 | -- | T | 50.61% | |
| rs12794371 | -- | T | 33.16% | |
| rs12930743 | -- | C | 55.15% | |
| rs12959642 | -- | G | 77.40% | |
| rs12960889 | -- | C | 56.81% | |
| rs13198298 | -- | T | 10.13% | |
| rs13217239 | -- | C | 36.45% | |
| rs13396259 | -- | G | 30.22% | |
| rs1452787 | -- | G | 28.43% | |
| rs1460939 | -- | T | 80.31% | |
| rs1484680 | -- | G | 58.25% | |
| rs1506 | -- | A | 80.61% | |
| rs1518395 | -- | G | 61.34% | |
| rs1558804 | -- | G | 45.10% | |
| rs164640 | -- | T | 52.97% | |
| rs17622606 | -- | A | 4.66% | |
| rs17782464 | -- | G | 15.65% | |
| rs1964390 | -- | G | 75.40% | |
| rs198457 | -- | T | 18.78% | |
| rs210915 | -- | T | 80.50% | |
| rs2191130 | -- | T | 68.27% | |
| rs2239549 | -- | A | 37.92% | |
| rs2290850 | -- | C | 34.82% | |
| rs2299502 | -- | C | 38.77% | |
| rs2342502 | -- | G | 46.13% | |
| rs2458167 | -- | C | 68.58% | |
| rs2690083 | -- | T | 34.54% | |
| rs2813608 | -- | A | 65.45% | |
| rs2919980 | -- | C | 51.41% | |
| rs297343 | -- | G | 63.71% | |
| rs308774 | -- | T | 20.38% | |
| rs3094669 | -- | G | 13.57% | |
| rs3115672 | -- | T | 11.36% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Baselmans BML, Jansen R, Ip HF, van Dongen J, Abdellaoui A, van de Weijer MP, Bao Y, Smart M, Kumari M, Willemsen G, Hottenga JJ, , , Boomsma DI, de Geus EJC, Nivard MG, Bartels M
Study sample: 80,852 individuals (european ancestry)
