Traits - Positive affect

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Positive affect

General

Positive affect research measures how often people experience pleasant emotions like joy, enthusiasm, or contentment.

GWAS work has identified variants linked to positive affect, with overlap with well-being and personality traits.

This result reflects research-level variation in mood-related traits and is not a clinical assessment.

Sleep, relationships, life events, mental health, and overall context strongly shape day-to-day positive emotion.

Selected sample
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Report markers
191 SNP entries
Genes
0
Research
1 study
Your report

Genetic tendency

Higher positive affect tendency

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Explore the evidence

Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs10891549CCC54.60%
rs10896633TCC31.32%
rs12791990TCC14.08%
rs17041417GAA18.07%
rs3936093AGG57.03%
rs4526571GAA38.30%
rs7396827CCC53.45%
rs9332801ACC6.34%
rs9546806CTT61.12%
rs9601116GAA18.34%
rs310763CCC78.44%
rs3134012CCC71.92%
rs3764512GTT22.55%
rs6771469CCC40.18%
rs6925748GGG42.05%
rs716508TTT68.24%
rs3793577AGG53.16%
rs10252771TGG31.97%
rs10818400GGG60.57%
rs1213048TCC41.83%
rs12552533GTT27.42%
rs1493914CTT51.35%
rs1660237CTT42.03%
rs495146CTT25.74%
rs769688TTT66.66%
rs7819525GTT42.28%
rs8053004TTT30.18%
rs815710AGG40.72%
rs2398144CAA40.43%
rs2715147CTT49.91%
rs10774909--G20.31%
rs10783484--T25.20%
rs10838629--A77.01%
rs10916951--T39.35%
rs12587457--T50.61%
rs12794371--T33.16%
rs12910872--T12.09%
rs12930743--C55.15%
rs1506--A80.61%
rs16958292--G13.54%
rs17186681--T19.85%
rs17782464--G15.65%
rs1939252--G47.62%
rs1950835--T51.27%
rs198457--T18.78%
rs215815--A29.90%
rs2290850--C34.82%
rs2296483--A63.85%
rs2458167--C68.58%
rs28680958--A21.68%
rs297346--G63.71%
rs308805--T20.30%
rs35368417--C44.04%
rs3767247--C37.42%
rs3781627--A69.41%
rs4146385--A56.81%
rs4337088--G56.91%
rs45599947--T7.45%
rs4581549--T11.72%
rs61905363--T3.89%
rs674437--A52.11%
rs7111031--A63.64%
rs7154329--G49.95%
rs77648771--T4.95%
rs7974375--T16.63%
rs7989827--G49.11%
rs8001600--C34.63%
rs888194--G44.98%
rs9564496--A31.84%
rs2893910--T18.78%
rs3115672--T11.36%
rs3130614--A11.92%
rs3132556--T18.43%
rs325501--C57.87%
rs34020413--G38.26%
rs35016036--T10.14%
rs35267052--G10.66%
rs35609938--C50.75%
rs35741362--C12.75%
rs3734572--C3.95%
rs3811935--G49.67%
rs11214441--A39.59%
rs12083196--C23.08%
rs12436091--C76.00%
rs6769821--A73.86%
rs6776145--C12.08%
rs68006638--A8.63%
rs6882578--C51.06%
rs6923139--T11.23%
rs6943746--G38.57%
rs71301807--G24.20%
rs7191427--T25.27%
rs7232516--A13.21%
rs7243332--G30.56%
rs7374731--G74.68%
rs7422667--C56.37%
rs2073526--A55.56%
rs2075677--G23.84%
rs210915--T80.50%
rs2149351--G75.89%
rs2179744--A29.16%
rs2239549--A37.92%
rs2296576--C66.91%
rs2342502--G46.13%
rs2371220--A51.77%
rs10740246--C59.47%
rs10967509--A37.94%
rs10974344--T39.34%
rs11192283--C23.40%
rs12236195--T20.03%
rs1490176--A71.51%
rs1964390--G75.40%
rs2093623--A48.87%
rs3824344--T37.29%
rs4554778--T80.20%
rs4914984--G76.95%
rs59925771--T10.52%
rs703410--A25.84%
rs10168771--A65.86%
rs10497655--C31.09%
rs10959560--T18.92%
rs111871194--C9.90%
rs112028067--A21.81%
rs114595701--T9.25%
rs1150757--A11.19%
rs115091345--C2.91%
rs116537337--G4.18%
rs11693031--G33.09%
rs1187219--C32.60%
rs11876796--T51.93%
rs12513440--A25.03%
rs12706745--T38.73%
rs12955614--C33.49%
rs12959642--G77.40%
rs12960889--C56.81%
rs12962538--C18.18%
rs13198298--T10.13%
rs13212534--A8.90%
rs13282477--C11.32%
rs13396259--G30.22%
rs13409834--G49.89%
rs1348049--G51.26%
rs1371325--G59.70%
rs1431071--T28.51%
rs1452787--G28.43%
rs1460939--T80.31%
rs1484680--G58.25%
rs149979--A22.98%
rs1518395--G61.34%
rs16003--T50.77%
rs164640--T52.97%
rs16826757--A35.16%
rs17049478--A7.30%
rs1714507--A55.98%
rs17417046--T44.32%
rs17583539--G22.45%
rs17622606--A4.66%
rs1884352--A60.71%
rs198856--A53.35%
rs2015971--T44.86%
rs4077277--T51.29%
rs4129585--C56.05%
rs4239724--G21.47%
rs4461738--C46.46%
rs4665238--A58.54%
rs4671459--C19.47%
rs4711152--C45.08%
rs55748329--G13.83%
rs6019826--T13.30%
rs6073995--G64.81%
rs619466--G90.22%
rs62553458--A6.01%
rs6442647--G29.09%
rs66993685--A23.08%
rs6721577--T58.36%
rs746839--G36.53%
rs7606466--G56.99%
rs77214504--T4.54%
rs7789405--T57.44%
rs7809934--C30.85%
rs8084280--T50.84%
rs876308--A41.70%
rs9295661--A92.16%
rs9348726--A12.43%
rs9380010--G25.02%
rs959932--C24.80%
rs9967747--C86.49%
rs2589341--C34.29%
rs263575--A45.20%
rs2690083--T34.54%
rs2865116--A66.92%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

Multivariate genome-wide analyses of the well-being spectrum

EvidenceVery strong scientific evidence

2019 Mar Nat Genet

Authors: Baselmans BML, Jansen R, Ip HF, van Dongen J, Abdellaoui A, van de Weijer MP, Bao Y, Smart M, Kumari M, Willemsen G, Hottenga JJ, , , Boomsma DI, de Geus EJC, Nivard MG, Bartels M

Study sample: 80,852 individuals (european ancestry)

Browse traits

Coverage: 30/191 SNP entries detected (15%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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