Traits - Genetic associations studied in anxiety-response research
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This research area looks at the anxiety and tension component of neuroticism, a Big Five personality dimension.
GWAS work has identified variants linked to self-reported anxiety and tension, with overlap with broader neuroticism, depression, and well-being traits.
This result reflects research-level variation in personality-related traits and is not a clinical anxiety diagnosis.
Stress, sleep, life events, relationships, mental health support, and overall context strongly shape how anxiety actually appears.
Research summary, not an individual result
This trait is presented as population-level genetic research rather than an individual Low/High verdict, because the science behind it is either too preliminary, too easily misread as a diagnosis, or too sensitive to responsibly reduce to a single badge.
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs3764002 | CT | T | 25.70% | |
| rs7526108 | GA | 23.54% | ||
| rs9829032 | AG | G | 38.10% | |
| rs10027492 | -- | 42.35% | ||
| rs11030088 | -- | A | 12.30% | |
| rs17175643 | -- | 78.89% | ||
| rs2458604 | -- | A | 40.02% | |
| rs28570522 | -- | 39.26% | ||
| rs3800227 | -- | 46.91% | ||
| rs3902934 | -- | 57.57% | ||
| rs4129585 | -- | 23.88% | ||
| rs8054556 | -- | 60.54% | ||
| rs10174328 | -- | 72.58% | ||
| rs2071044 | -- | 44.73% | ||
| rs2672852 | -- | 45.61% | ||
| rs4856278 | -- | 16.75% | ||
| rs76508707 | -- | T | 45.33% | |
| rs7652808 | -- | 24.26% | ||
| rs77165542 | -- | 98.96% | ||
| rs9828679 | -- | C | 11.28% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Hill WD, Weiss A, Liewald DC, Davies G, Porteous DJ, Hayward C, McIntosh AM, Gale CR, Deary IJ
Study sample: 270,059 individuals (european ancestry)
