Traits - Environmental-stress-response tendency
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This research area looks at inherited differences in how strongly people respond to environmental stress and adversity, sometimes framed as differential susceptibility.
GWAS work has identified some variants linked to stress sensitivity, with overlap with neuroticism and depression traits.
This result reflects research-level variation in stress-related traits and is not a clinical assessment.
Type and severity of stressors, social support, prior experience, mental health, and coping strategies strongly shape actual responses.
Choose whether to view this association. The evidence and its limitations remain available below.
Average genetic tendency
This is a weak, population-level genetic association, not a personal diagnosis or a definitive trait.
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs10119773 | AG | G | 49.64% | |
| rs11167957 | TT | T | 48.02% | |
| rs4791331 | TT | T | 48.38% | |
| rs6941112 | GA | A | 22.68% | |
| rs9811585 | GG | G | 44.35% | |
| rs10476484 | -- | G | 47.92% | |
| rs10765820 | -- | 54.75% | ||
| rs11022762 | -- | T | 49.00% | |
| rs11090045 | -- | A | 21.29% | |
| rs11115117 | -- | C | 11.38% | |
| rs11263943 | -- | G | 42.27% | |
| rs11613183 | -- | C | 10.94% | |
| rs11627348 | -- | A | 11.48% | |
| rs1941355 | -- | 50.14% | ||
| rs1978573 | -- | T | 33.25% | |
| rs2186710 | -- | G | 61.12% | |
| rs2282040 | -- | G | 8.75% | |
| rs2305411 | -- | 42.05% | ||
| rs2407746 | -- | G | 22.56% | |
| rs2627019 | -- | 36.22% | ||
| rs3124426 | -- | 40.00% | ||
| rs314289 | -- | 50.56% | ||
| rs34351088 | -- | C | 26.08% | |
| rs34657012 | -- | A | 18.17% | |
| rs35393419 | -- | T | 18.43% | |
| rs35738585 | -- | G | 32.63% | |
| rs3772882 | -- | A | 54.09% | |
| rs3785237 | -- | 70.33% | ||
| rs391957 | -- | 25.82% | ||
| rs45601232 | -- | G | 0.34% | |
| rs527528 | -- | T | 25.26% | |
| rs56084168 | -- | T | 16.49% | |
| rs62442206 | -- | C | 9.68% | |
| rs6439649 | -- | 43.93% | ||
| rs6490177 | -- | A | 25.90% | |
| rs7567451 | -- | T | 56.67% | |
| rs75737648 | -- | T | 7.97% | |
| rs761898 | -- | 13.26% | ||
| rs80143279 | -- | C | 8.61% | |
| rs8045843 | -- | 54.39% | ||
| rs9366697 | -- | C | 50.14% | |
| rs9462364 | -- | G | 30.97% | |
| rs11665070 | -- | A | 48.66% | |
| rs1282545 | -- | C | 59.33% | |
| rs13070517 | -- | T | 26.24% | |
| rs13284170 | -- | A | 25.68% | |
| rs17049509 | -- | T | 41.81% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Nagel M, Speed D, van der Sluis S, Østergaard SD
Study sample: 351,827 individuals (european ancestry)
