Traits - Bunions susceptibility
Download PDF creates a visual, rasterized copy. Use Print for selectable text and better assistive-technology support.
Hallux valgus (bunions) is a deformity of the joint at the base of the big toe, with strong heritable and biomechanical contributions.
GWAS work has identified variants linked to bunion susceptibility, often near genes involved in foot development.
This result reflects research-level variation in foot biology and is not a clinical diagnosis.
Footwear, foot biomechanics, body weight, age, and prior injuries all strongly affect actual bunion development.
Average genetic tendency
Was this result accurate for you?
Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs4811981 | TT | 30.00% | ||
| rs347133 | AA | 26.00% | ||
| rs11707593 | -- | T | 24.00% | |
| rs2631419 | -- | T | 32.00% | |
| rs71218579 | -- | 68.00% | ||
| rs76655016 | -- | A | 1.00% | |
| rs77993129 | -- | C | 97.00% | |
| rs79147928 | -- | A | 86.00% | |
| rs80177909 | -- | G | 98.00% | |
| rs11868764 | -- | G | 3.00% | |
| rs113871023 | -- | T | 99.00% | |
| rs116783165 | -- | C | 3.00% | |
| rs117155606 | -- | T | 1.00% | |
| rs11728629 | -- | A | 24.00% | |
| rs117974989 | -- | A | 99.00% | |
| rs12143200 | -- | G | 3.00% | |
| rs12888772 | -- | 18.00% | ||
| rs140687271 | -- | A | 99.00% | |
| rs146496015 | -- | T | 6.00% | |
| rs58302722 | -- | A | 2.00% | |
| rs12619631 | -- | A | 15.00% | |
| rs539720802 | -- | T | 99.00% | |
| rs13147821 | -- | 26.00% | ||
| rs139705512 | -- | A | 2.00% | |
| rs116712252 | -- | A | 99.00% | |
| chr18:50130115 | -- | 2.00% | ||
| chr8:52512282 | -- | 1.00% | ||
| rs10176968 | -- | A | 39.00% | |
| rs140676665 | -- | 99.00% | ||
| rs141161671 | -- | A | 1.00% | |
| rs142973841 | -- | T | 2.00% | |
| rs145025296 | -- | C | 2.00% | |
| rs1859504 | -- | C | 32.00% | |
| rs188650377 | -- | T | 1.00% | |
| rs191124187 | -- | C | 1.00% | |
| rs28395286 | -- | T | 5.00% | |
| rs3891969 | -- | A | 15.00% | |
| rs55807512 | -- | C | 4.00% | |
| rs6733149 | -- | C | 1.00% | |
| rs72762109 | -- | G | 1.00% | |
| rs74863661 | -- | T | 15.00% | |
| rs78762426 | -- | A | 8.00% | |
| rs9850315 | -- | C | 2.00% | |
| rs150013648 | -- | T | 2.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Arbeeva L, Yau M, Mitchell BD, Jackson RD, Ryan K, Golightly YM, Hannan MT, Nelson A, Jordan JM, Hochberg MC
Study sample: 2,275 individuals (european ancestry)
