Traits - Smell sensitivity
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Smell sensitivity covers research on inherited differences in how strongly people detect a wide range of odors.
GWAS work has identified variants in olfactory receptor genes that influence detection thresholds for specific compounds.
This result reflects research-level variation in olfactory biology and is not a clinical smell test.
Age, smoking, head injury, recent illness (including viral infections), nasal health, and exposure history all strongly affect real smell sensitivity.
Average genetic tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs12291225 | CA | A | 25.00% | |
| rs2075650 | AG | 13.00% | ||
| rs2251885 | AG | 37.00% | ||
| rs6052484 | GA | A | 26.00% | |
| rs11174650 | -- | T | 8.00% | |
| rs16875528 | -- | C | 1.00% | |
| rs17252438 | -- | 5.00% | ||
| rs199443 | -- | T | 20.00% | |
| rs2732614 | -- | T | 20.00% | |
| rs3751196 | -- | A | 6.00% | |
| rs4111 | -- | C | 15.00% | |
| rs4715057 | -- | G | 2.00% | |
| rs4865875 | -- | 9.00% | ||
| rs605843 | -- | 25.00% | ||
| rs9321099 | -- | A | 9.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H
Study sample: 6,252 individuals (european ancestry)
