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Sweetness detection

Taste & Smell

Sweetness detection covers inherited differences in how strongly sweet flavors are perceived on the tongue.

Variants in the sweet taste receptor genes (TAS1R2 and TAS1R3) have been linked to differences in sweet perception.

This result reflects research-level variation in taste biology and is not a clinical taste test.

Diet, age, smoking, oral health, and food culture also strongly affect how sweetness is perceived in everyday eating.

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Selected sample: Demo Report
Report markers: 3 SNP entries
Genes: 1
Research: 1 study

Important Medical Disclaimer

This report is intended for educational and informational purposes only. It is not intended to provide medical advice or be used solely by the customer in the diagnosis, cure, mitigation, treatment, or prevention of any disease or health condition. If you have serious medical conditions, including but not limited to weight-related issues, diabetes, or heart disease, you should not make changes to your diet or exercise routine without consulting your healthcare provider. Under no circumstances should you modify your medication or medical care without professional medical guidance. Find more information at this link

Your report

Genetic tendency

Average ability to detect sweetness

Very Low Very High

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Evidence and coverage

Confidence score

Very high

Read the evidence rating alongside the markers detected in your file. Confidence and tendency describe different aspects of this report.

Markers detected3 / 3100% coverage of report entries

Trait influence breakdown

Genetic 80% 80% Environment 20% 20%

Explore the evidence

Behind this report

Review the genes, tested markers and supporting research.

Genes analyzed

Gene summaries include genomic locations and associated markers. A detected genotype does not by itself indicate a health condition.

Understanding the data

SNP: A specific genetic marker relevant to this trait.
Genotype: The DNA letters reported at a marker location.
Variant allele: The alternative DNA sequence at the SNP site.
Variant allele frequency: The reported percentage of the reference population carrying this variant.
Variant found: Whether the variant was detected in your DNA file.

1 of 1 genes have detected genotypes.

TAS1R3

The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]

GeneCards

Chromosome: 1
Start: 1,331,280
End: 1,335,320
Build: HG19

Associated SNPs 1 / 1 detected

Associated markers for TAS1R3
SNP	Genotype	Ref. allele	Variant allele	Frequency	Status
rs35744813	CC	T	C	71.57%	Detected

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNP	Chromosome	Genotype	Variant allele	Frequency
rs35744813	1	CC	C	71.57%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose

Evidence

Statistical significance

08/11/2009

Authors: Fushan AA, Simons CT, Slack JP, Manichaikul A, Drayna D