Traits - Photic sneeze reflex
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Photic sneeze reflex (autosomal dominant compelling helio-ophthalmic outburst, or ACHOO) describes sneezing in response to bright light.
GWAS work has identified a variant near the ZEB2 gene linked to the trait, which affects an estimated 18-35 percent of people.
This result reflects research-level variation in this reflex and is not a clinical evaluation.
Light intensity and abrupt light exposure are the main triggers in real life.
Increased odds of having the photic sneeze reflex
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs10427255 | 2 | TT | T | 56.33% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
06/24/2010 PLoS Genet
Authors: Eriksson N, Macpherson JM, Tung JY, Hon LS, Naughton B, Saxonov S, Avey L, Wojcicki A, Pe', er I, Mountain J
Study sample: 9,126 individuals (european ancestry)
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