Genetic associations studied in sun-sensitivity research

Sun Protection

Skin sensitivity to sun is closely tied to pigmentation biology and reflects how easily skin reddens or burns after UV exposure.

Variants in MC1R, ASIP, TYR, and other pigmentation genes are strongly linked to skin sensitivity, hair color, and freckling.

This result reflects research-level variation in skin biology and is not a measurement of safe sun exposure for any individual.

Time of day, latitude, altitude, water reflection, sunscreen use, clothing, and prior tanning all strongly affect actual sunburn risk.

All traits Compare samples

Selected sample: Demo Report
Report markers: 2 SNP entries
Genes: 0
Research: 1 study

Important Medical Disclaimer

This report is intended for educational and informational purposes only. It is not intended to provide medical advice or be used solely by the customer in the diagnosis, cure, mitigation, treatment, or prevention of any disease or health condition. If you have serious medical conditions, including but not limited to weight-related issues, diabetes, or heart disease, you should not make changes to your diet or exercise routine without consulting your healthcare provider. Under no circumstances should you modify your medication or medical care without professional medical guidance. Find more information at this link

Research summary

What this trait studies

Research summary, not an individual result

This trait is presented as population-level genetic research rather than an individual Low/High verdict, because the science behind it is either too preliminary, too easily misread as a diagnosis, or too sensitive to responsibly reduce to a single badge.

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Explore the evidence

Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNP	Chromosome	Genotype	Variant allele	Frequency
rs1393350		GA	A	27.00%
rs1805007		--	T	6.00%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

Genetic determinants of hair, eye and skin pigmentation in Europeans

Evidence

Very strong scientific evidence

2007 Dec Nat Genet

Authors: Sulem P, Gudbjartsson DF, Stacey SN, Helgason A, Rafnar T, Magnusson KP, Manolescu A, Karason A, Palsson A, Thorleifsson G, Jakobsdottir M, Steinberg S, Pálsson S, Jonasson F, Sigurgeirsson B, Thorisdottir K, Ragnarsson R, Benediktsdottir KR, Aben KK, Kiemeney LA, Olafsson JH, Gulcher J, Kong A, Thorsteinsdottir U, Stefansson K

Study sample: 2,986 individuals (european ancestry)