Traits - Scar healing quality
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Keloids are raised scars that grow beyond the original wound boundary because of excess collagen production during healing.
GWAS work has identified variants linked to keloid susceptibility, with notably higher prevalence in people of African and Asian ancestry.
This result reflects research-level variation in scar biology and is not a diagnosis or a treatment recommendation.
Wound location (chest, shoulders, earlobes), wound depth, age, infections, and prior keloid history also play a large role.
Average genetic tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs1511412 | GG | 8.00% | ||
| rs8032158 | TC | C | 36.00% | |
| rs873549 | TT | 28.00% | ||
| rs11130248 | -- | 52.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
2010 Sep Nat Genet
Authors: Nakashima M, Chung S, Takahashi A, Kamatani N, Kawaguchi T, Tsunoda T, Hosono N, Kubo M, Nakamura Y, Zembutsu H
Study sample: 1,122 individuals (east asian ancestry)
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