Traits - Skin youthfulness

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Skin youthfulness

Aging & Appearance

Skin aging is studied in research using microtopography (fine wrinkles, surface roughness) and other measurable skin features that change with age and sun exposure.

GWAS work has identified variants near pigmentation, collagen, and DNA-repair genes linked to differences in visible skin aging.

This result reflects research-level variation in skin-aging traits and is not a forecast of how youthful skin will look.

Sun exposure, smoking, sleep, hydration, skincare, hormones, and overall health are major drivers of how skin actually ages over time.

Selected sample
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Report markers
14 SNP entries
Genes
0
Research
1 study
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Genetic tendency

Average genetic tendency

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Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs4698048GGG61.00%
rs13020412AGG3.00%
rs96621TC51.88%
rs4268748--C71.00%
rs428668--C47.76%
18:69333415--0.00%
2:211327945--0.00%
rs10445747--G2.76%
rs12203592--G79.00%
rs12661968--C17.35%
rs185146--T94.00%
rs9848726--T32.27%
rs35096708--88.52%
rs3791406--T56.71%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

Research studies

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

2017 Sep J Invest Dermatol

Authors: Law MH, Medland SE, Zhu G, Yazar S, Viñuela A, Wallace L, Shekar SN, Duffy DL, Bataille V, Glass D, Spector TD, Wood D, , Gordon SD, Barbour JM, Henders AK, Hewitt AW, Montgomery GW, Sturm RA, Mackey DA, Green AC, Martin NG, MacGregor S

Study sample: 5,087 individuals (nr ancestry)

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Coverage: 3/14 SNP entries detected (21%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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