Traits - Wrinkle resistance
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Facial wrinkles are creases that develop in the skin over time due to a mix of intrinsic aging and external damage.
GWAS work has identified variants near collagen, elastin, and pigmentation genes linked to differences in visible facial wrinkles.
This result reflects research-level variation in wrinkle biology and is not a forecast of future skin appearance.
Sun exposure, smoking, hydration, expression patterns, sleep position, skincare, and overall skin health all play a large role in how wrinkles develop.
Average genetic tendency
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Review the genes, tested markers and supporting research.
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs11711327 | GA | A | 65.00% | |
| rs117828793 | CT | T | 3.00% | |
| rs1283106 | CA | A | 37.00% | |
| rs702491 | TC | 20.00% | ||
| rs78569750 | -- | T | 6.00% | |
| chr10:25869856 | -- | 0.00% | ||
| rs10476781 | -- | C | 94.00% | |
| rs11213999 | -- | A | 8.00% | |
| rs113322056 | -- | G | 96.00% | |
| rs1150997 | -- | 72.00% | ||
| rs116248825 | -- | A | 4.00% | |
| rs116873518 | -- | C | 2.00% | |
| rs1225927 | -- | 75.00% | ||
| rs147672305 | -- | A | 2.00% | |
| rs184605088 | -- | A | 2.00% | |
| rs184880542 | -- | T | 2.00% | |
| rs62047859 | -- | A | 3.00% | |
| rs6429657 | -- | A | 96.00% | |
| rs72811030 | -- | A | 38.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
Authors: Hamer MA, Pardo LM, Jacobs LC, Deelen J, Uitterlinden AG, Slagboom E, van Heemst D, Uh HW, Beekman M, Kayser M, Liu F, Gunn DA, Nijsten T
Study sample: 599 individuals (european ancestry)
