Traits - Varicose veins susceptibility

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Varicose veins susceptibility

Aging & Appearance

Varicose veins are enlarged, twisted veins that often appear in the legs and have a strong inherited component.

GWAS work has identified variants near genes involved in vein wall structure and venous valve function (such as CASZ1 and EBF1) linked to varicose vein risk.

This result reflects research-level variation in vein biology and is not a clinical diagnosis.

Pregnancy, prolonged standing, body weight, age, hormones, and prior leg injuries all strongly affect actual varicose vein development.

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30 SNP entries
Genes
0
Research
0 studies
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Genetic tendency

Average genetic tendency

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Behind this report

Review the genes, tested markers and supporting research.

SNPs tested

These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.

Genotypes and reported variant frequencies
SNPChromosomeGenotypeVariant alleleFrequency
rs11121615TTT69.00%
rs236597TTT74.00%
rs7773004AGG49.00%
rs11135046--T54.00%
rs12594708--T7.60%
rs12625547--G18.00%
rs1549063--T36.00%
rs16828263--C0.06%
rs186005582--T0.03%
chr6:127452639--50.00%
rs1061539--C83.00%
rs2263321--A33.00%
rs247749--C29.00%
rs28558138--C42.00%
rs2861819--C65.00%
rs2911463--A69.00%
rs3101725--C76.00%
rs553399706--A0.06%
rs584768--A53.00%
rs62512472--A43.00%
rs73107980--T24.00%
rs7469817--C74.00%
rs75522736--G16.00%
rs7614922--C14.00%
rs8053350--A56.00%
rs816943--G48.00%
rs9719461--T66.00%
rs192647746--G0.11%
rs2089657--T21.00%
rs2241173--G58.00%

DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.

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Coverage: 3/30 SNP entries detected (10%).

Reference: Human Genome Build 37 (HG19). Other testing companies may report using the opposite strand, requiring conversion for comparison.

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