Varicose veins susceptibility
Aging & AppearanceVaricose veins are enlarged, twisted veins that often appear in the legs and have a strong inherited component.
GWAS work has identified variants near genes involved in vein wall structure and venous valve function (such as CASZ1 and EBF1) linked to varicose vein risk.
This result reflects research-level variation in vein biology and is not a clinical diagnosis.
Pregnancy, prolonged standing, body weight, age, hormones, and prior leg injuries all strongly affect actual varicose vein development.
- Selected sample
- Demo Report
- Report markers
- 30 SNP entries
- Genes
- 0
- Research
- 0 studies
Genetic tendency
Average genetic tendency
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Behind this report
Review the genes, tested markers and supporting research.
SNPs tested
These are the unique genetic markers analyzed for this trait. Genotypes showing "--" were not identified in your DNA file. Report marker totals can include repeated study entries; this table shows each SNP once.
| SNP | Chromosome | Genotype | Variant allele | Frequency |
|---|---|---|---|---|
| rs11121615 | TT | T | 69.00% | |
| rs236597 | TT | T | 74.00% | |
| rs7773004 | AG | G | 49.00% | |
| rs11135046 | -- | T | 54.00% | |
| rs12594708 | -- | T | 7.60% | |
| rs12625547 | -- | G | 18.00% | |
| rs1549063 | -- | T | 36.00% | |
| rs16828263 | -- | C | 0.06% | |
| rs186005582 | -- | T | 0.03% | |
| chr6:127452639 | -- | 50.00% | ||
| rs1061539 | -- | C | 83.00% | |
| rs2263321 | -- | A | 33.00% | |
| rs247749 | -- | C | 29.00% | |
| rs28558138 | -- | C | 42.00% | |
| rs2861819 | -- | C | 65.00% | |
| rs2911463 | -- | A | 69.00% | |
| rs3101725 | -- | C | 76.00% | |
| rs553399706 | -- | A | 0.06% | |
| rs584768 | -- | A | 53.00% | |
| rs62512472 | -- | A | 43.00% | |
| rs73107980 | -- | T | 24.00% | |
| rs7469817 | -- | C | 74.00% | |
| rs75522736 | -- | G | 16.00% | |
| rs7614922 | -- | C | 14.00% | |
| rs8053350 | -- | A | 56.00% | |
| rs816943 | -- | G | 48.00% | |
| rs9719461 | -- | T | 66.00% | |
| rs192647746 | -- | G | 0.11% | |
| rs2089657 | -- | T | 21.00% | |
| rs2241173 | -- | G | 58.00% |
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence (build 37/HG19). Other companies may use the opposite strand, so genotypes may need conversion for comparison.