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Portrait reconstruction of R1289
Ancient Individual

A woman buried in Italy in the Middle Ages era

R1289
1350 CE - 1500 CE
Female
Medieval to Early Modern Italy
Italy
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Chapter I

Identity

The biological and cultural markers that define this ancient individual

Sample ID

R1289

Date Range

1350 CE - 1500 CE

Biological Sex

Female

mtDNA Haplogroup

K1a4a1

Cultural Period

Medieval to Early Modern Italy

Chapter II

Place

Where this individual was discovered

Country Italy
Locality Cancelleria
Coordinates 41.8965, 12.4719
Chapter III

Time

When this individual lived in the broader context of human history

R1289 1350 CE - 1500 CE
Chapter IV

Story

The narrative of this ancient life

The transition from Medieval to Early Modern Italy covers a period from approximately the 11th century to the 17th century, marked by profound social, political, cultural, and economic transformations. Italy during this era was not a unified nation, but a patchwork of city-states, territories, and regions, each with its own government, culture, and socio-economic dynamics. This period witnessed the rise of powerful city-states such as Florence, Venice, Genoa, and Milan, as well as the Papal States, which significantly influenced the cultural and political landscapes of the era.

Medieval Italy: 11th to 13th Century

Political Landscape: During the early medieval period, Italy was a fragmented collection of duchies and principalities. The Holy Roman Empire wielded considerable influence, particularly in the north, leading to frequent conflicts between imperial and papal forces. The Investiture Controversy, a conflict between secular and religious powers, played out prominently in Italy, affecting its political stability.

Economic Development: Italy’s strategic location and its numerous ports fostered trade networks that extended across the Mediterranean and into the East. This period saw the emergence of powerful merchant and banking families. The Venetians and Genoese established extensive maritime empires, acting as crucial intermediaries in the trade between Europe and the Levant.

Cultural and Social Aspects: The cities of Italy became centers of commerce and culture, fostering the growth of a merchant class that would later play a crucial role in the Renaissance. The burgeoning cities built grand cathedrals and established universities that became centers of learning. The use of Roman law was revitalized, leading to advances in legal scholarship.

Transition to the Early Modern Period: 14th to 15th Century

The Renaissance: The Renaissance began in Italy during the 14th century, marking a renewed interest in classical antiquity's literature, philosophy, and arts. Florence became the heart of the Renaissance, home to great artists such as Leonardo da Vinci, Michelangelo, and Raphael, supported by patrons like the Medici family. Humanism emerged as a defining intellectual movement, emphasizing the potential and achievements of humans.

Political Shifts: As the Medieval era waned, Italy became a battleground for European powers. The Italian Wars (1494–1559) among France, Spain, and the Holy Roman Empire dramatically altered Italy’s political map, leading to the decline of some city-states and the rise of others, like the Spanish-dominated Kingdom of Naples.

Economic Changes: The economy of Italy during this time experienced significant changes. The decline of feudalism, rise of urban centers, and expansion of trade networks all contributed to a growing economy. Banking families like the Medici and the Bardi rose to prominence, pioneering modern finance techniques.

Social Structure: The period saw a shift in social structures. The growth of trade and urbanization led to the decline of feudal power structures, replaced by more oligarchic and, in some cases, republican forms of government. However, these governments were often dominated by powerful families.

Early Modern Italy: 16th to 17th Century

Cultural Flourishing and Challenges: The artistic and intellectual advancements of the Renaissance continued into the 16th century, with Mannerism and later Baroque art becoming prominent. The religious landscape shifted with the Protestant Reformation, leading to the Catholic Counter-Reformation, which saw the Church reaffirm its influence and power.

Scientific and Intellectual Growth: Italy contributed significantly to the Scientific Revolution of the 16th and 17th centuries. Figures such as Galileo Galilei played crucial roles in advancing astronomical and physical sciences.

Political Context: The political context remained complex, with foreign powers having substantial influence. The Peace of Cateau-Cambrésis in 1559 ended most of the Italian Wars, leaving Spain in control of much of southern Italy and Lombardy. The Papacy also asserted its authority, both spiritually and politically, within the Papal States and beyond.

Economic and Social Shifts: Although commerce was still significant, Italy began to lose its supremacy as trade routes shifted towards the Atlantic. This shift, combined with the costs of constant warfare, led to economic challenges. Despite these struggles, Italy continued to influence Europe culturally and intellectually.

Overall, the era from Medieval to Early Modern Italy was one of extraordinary achievements and profound transformations. Despite political fragmentation and frequent warfare, Italy emerged as a cultural beacon, laying the intellectual and artistic groundwork that would shape the modern Western world.

Chapter V

Genetics

The genetic ancestry of this ancient individual

Ancient Genetic Admixture

This analysis compares the DNA profile of R1289 with ancient reference populations, showing the genetic composition in terms of prehistoric ancestral groups.

European Hunter-Gatherers 39.1%
Neolithic Farmers 32.0%
Western Steppe Pastoralists 28.8%

Modern Genetic Admixture

This analysis compares the DNA profile with present-day reference populations, showing what percentage of genetic makeup resembles modern populations from different regions.

Europe 96.8%
Southern European 68.5%
Iberian 45.2%
Italian 13.7%
Balkan 8.3%
Sardinian 1.3%
Northwestern European 28.4%
English 18.9%
Northwestern European 9.4%
Asia 1.6%
Northern West Asian 0.9%
Cypriot 0.9%
Central Asian, Northern Indian & Pakistani 0.7%
Indian 0.7%
Africa 0.9%
North African 0.6%
North African 0.6%
America 0.7%
America 0.7%
Native American 0.7%

Closest Modern Populations

These are the modern populations showing the closest statistical alignment to A woman buried in Italy in the Middle Ages era, ranked by genetic distance. Lower distance values indicate closer statistical similarity.

1
Spanish Castilla Y Leon
1.7196
2
Spanish Cantabria
1.9098
3
Spanish Valencia
1.9178
4
Spanish Castilla La Mancha
1.9582
5
Spanish Aragon
2.0223
6
Spanish Galicia
2.0562
7
Spanish Andalucia
2.0734
8
Spanish Barcelones
2.0986
9
Spanish Pirineu
2.2176
10
Spanish Alacant
2.2274
Chapter VI

Context

Other ancient individuals connected to this sample

Sources

References

Scientific publications and genetic data

Scientific Publication

Ancient Rome: A genetic crossroads of Europe and the Mediterranean

Authors Antonio ML, Gao Z, Moots HM
Abstract

Ancient Rome was the capital of an empire of ~70 million inhabitants, but little is known about the genetics of ancient Romans. Here we present 127 genomes from 29 archaeological sites in and around Rome, spanning the past 12,000 years. We observe two major prehistoric ancestry transitions: one with the introduction of farming and another prior to the Iron Age. By the founding of Rome, the genetic composition of the region approximated that of modern Mediterranean populations. During the Imperial period, Rome's population received net immigration from the Near East, followed by an increase in genetic contributions from Europe. These ancestry shifts mirrored the geopolitical affiliations of Rome and were accompanied by marked interindividual diversity, reflecting gene flow from across the Mediterranean, Europe, and North Africa.

G25 Coordinates

The G25 coordinates for sample R1289 can be used for detailed admixture analysis in our G25 Studio tool.

R1289,0.1126302,0.14267652,0.04564054,0.00194312,0.04499858,0.0012364,-0.00325126,0.00093144,0.02818914,0.03218848,-0.0070324,0.0110271,-0.016014,-0.0092511,0.01306448,-0.00538868,-0.01447082,-0.0006759,-0.00270412,-0.00784704,0.00238418,8.644E-05,-0.0029192,-0.00761,-0.00292959
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