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GWAS Study

Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder.

Neale BM, Medland SE, Ripke S et al.

20732625 PubMed ID
GWAS Study Type
5415 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NB
Neale BM
MS
Medland SE
RS
Ripke S
AP
Asherson P
FB
Franke B
LK
Lesch KP
FS
Faraone SV
NT
Nguyen TT
SH
Schäfer H
HP
Holmans P
DM
Daly M
SH
Steinhausen HC
FC
Freitag C
RA
Reif A
RT
Renner TJ
RM
Romanos M
RJ
Romanos J
WS
Walitza S
WA
Warnke A
MJ
Meyer J
PH
Palmason H
BJ
Buitelaar J
VA
Vasquez AA
LN
Lambregts-Rommelse N
GM
Gill M
AR
Anney RJ
LK
Langely K
OM
O'Donovan M
WN
Williams N
OM
Owen M
TA
Thapar A
KL
Kent L
SJ
Sergeant J
RH
Roeyers H
ME
Mick E
BJ
Biederman J
DA
Doyle A
SS
Smalley S
LS
Loo S
HH
Hakonarson H
EJ
Elia J
TA
Todorov A
MA
Miranda A
MF
Mulas F
ER
Ebstein RP
RA
Rothenberger A
BT
Banaschewski T
OR
Oades RD
SE
Sonuga-Barke E
MJ
McGough J
NL
Nisenbaum L
MF
Middleton F
HX
Hu X
NS
Nelson S
Chapter II

Abstract

Summary of the research findings

Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of existing studies to boost statistical power.

2,064 European ancestry trios, 896 European ancestry cases, 2,455 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

5415
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., Israel, Netherlands, Belgium, Germany, U.K., Switzerland, Spain, Republic of Ireland
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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