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GWAS Study

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

Dichgans M, Malik R, König IR et al.

24262325 PubMed ID
GWAS Study Type
109126 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DM
Dichgans M
MR
Malik R
KI
König IR
RJ
Rosand J
CR
Clarke R
GS
Gretarsdottir S
TG
Thorleifsson G
MB
Mitchell BD
AT
Assimes TL
LC
Levi C
OC
O'Donnell CJ
FM
Fornage M
TU
Thorsteinsdottir U
PB
Psaty BM
HC
Hengstenberg C
SS
Seshadri S
EJ
Erdmann J
BJ
Bis JC
PA
Peters A
BG
Boncoraglio GB
MW
März W
MJ
Meschia JF
KS
Kathiresan S
IM
Ikram MA
MR
McPherson R
SK
Stefansson K
SC
Sudlow C
RM
Reilly MP
TJ
Thompson JR
SP
Sharma P
HJ
Hopewell JC
CJ
Chambers JC
WH
Watkins H
RP
Rothwell PM
RR
Roberts R
MH
Markus HS
SN
Samani NJ
FM
Farrall M
SH
Schunkert H
Chapter II

Abstract

Summary of the research findings

Background and purpose: Ischemic stroke (IS) and coronary artery disease (CAD) share several risk factors and each has a substantial heritability. We conducted a genome-wide analysis to evaluate the extent of shared genetic determination of the two diseases.

33,398 cases, 75,726 controls

Chapter III

Study Statistics

Key metrics and study information

109126
Total Participants
GWAS
Study Type
No
Replicated
Chapter IV

AI-Generated Summary

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