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GWAS Study

Investigation of the Predisposing Factor of Pemphigus and its clinical subtype through a Genome-wide association and next generation sequence analysis.

Sun Y, Liu H, Yang B et al.

30169916 PubMed ID
GWAS Study Type
1997 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SY
Sun Y
LH
Liu H
YB
Yang B
WC
Wang C
FJ
Foo JN
BF
Bao F
IA
Irwanto A
YG
Yu G
FX
Fu X
WZ
Wang Z
YJ
You J
LJ
Liu J
ZG
Zhou G
LJ
Liu J
ZF
Zhang F
Chapter II

Abstract

Summary of the research findings

Pemphigus is an autoimmune blistering disease with pemphigus vulgaris (PV) and foliaceus (PF) as the two major histological subtypes. Associations with HLA molecules have been suggested, but specific HLA risk variants as well as non-HLA risk variants remain to be discovered.

101 Chinese ancestry cases, 844 Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1997
Total Participants
GWAS
Study Type
Yes
Replicated
at least 56 Chinese ancestry cases, up to 996 Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

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