Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.
Winkler TW, Grassmann F, Brandl C et al.
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Abstract
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Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD.
14,034 European ancestry cases, 91,214 European ancestry controls
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