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GWAS Study

Genetic architecture of cardiometabolic risks in people living with HIV.

Cheng H, Sewda A, Marquez-Luna C et al.

33109212 PubMed ID
GWAS Study Type
6284 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CH
Cheng H
SA
Sewda A
MC
Marquez-Luna C
WS
White SR
WB
Whitney BM
WJ
Williams-Nguyen J
NR
Nance RM
LW
Lee WJ
KM
Kitahata MM
SM
Saag MS
WA
Willig A
EJ
Eron JJ
MW
Mathews WC
HP
Hunt PW
MR
Moore RD
WA
Webel A
MK
Mayer KH
DJ
Delaney JA
CP
Crane PK
CH
Crane HM
HK
Hao K
PI
Peter I
Chapter II

Abstract

Summary of the research findings

Advances in antiretroviral therapies have greatly improved the survival of people living with human immunodeficiency virus (HIV) infection (PLWH); yet, PLWH have a higher risk of cardiovascular disease than those without HIV. While numerous genetic loci have been linked to cardiometabolic risk in the general population, genetic predictors of the excessive risk in PLWH are largely unknown.

3,095 European ancestry individuals, 3,189 African American individuals

Chapter III

Study Statistics

Key metrics and study information

6284
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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