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Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23.

Garnier S, Harakalova M, Weiss S et al.

33677556 PubMed ID
GWAS Study Type
8527 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GS
Garnier S
HM
Harakalova M
WS
Weiss S
MM
Mokry M
RV
Regitz-Zagrosek V
HC
Hengstenberg C
CT
Cappola TP
IR
Isnard R
AE
Arbustini E
CS
Cook SA
VS
van Setten J
CJ
Calis JJA
HH
Hakonarson H
MM
Morley MP
SK
Stark K
PS
Prasad SK
LJ
Li J
OD
O'Regan DP
GM
Grasso M
MM
Müller-Nurasyid M
MT
Meitinger T
EJ
Empana JP
SK
Strauch K
WM
Waldenberger M
MK
Marguiles KB
SC
Seidman CE
KG
Kararigas G
MB
Meder B
HJ
Haas J
BP
Boutouyrie P
LP
Lacolley P
JX
Jouven X
EJ
Erdmann J
BS
Blankenberg S
WT
Wichter T
RV
Ruppert V
TL
Tavazzi L
DO
Dubourg O
RG
Roizes G
DR
Dorent R
DG
de Groote P
FL
Fauchier L
TJ
Trochu JN
AJ
Aupetit JF
BZ
Bilinska ZT
GM
Germain M
VU
Völker U
HD
Hemerich D
RI
Raji I
BD
Bacq-Daian D
PC
Proust C
RP
Remior P
GM
Gomez-Bueno M
LK
Lehnert K
MR
Maas R
OR
Olaso R
SG
Saripella GV
FS
Felix SB
MS
McGinn S
DL
Duboscq-Bidot L
VM
van Mil A
BC
Besse C
FV
Fontaine V
BH
Blanché H
AF
Ader F
KB
Keating B
CA
Curjol A
BA
Boland A
KM
Komajda M
CF
Cambien F
DJ
Deleuze JF
DM
Dörr M
AF
Asselbergs FW
VE
Villard E
TD
Trégouët DA
CP
Charron P
Chapter II

Abstract

Summary of the research findings

Aims: Our objective was to better understand the genetic bases of dilated cardiomyopathy (DCM), a leading cause of systolic heart failure.

2,651 European ancestry cases, 4,329 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

8527
Total Participants
GWAS
Study Type
Yes
Replicated
584 European ancestry cases, 963 European ancestry controls
Replication Participants
European
Ancestry
France, Germany, Italy, U.K., U.S., Netherlands
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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