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GWAS Study

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Cade BE, Lee J, Sofer T et al.

34446064 PubMed ID
GWAS Study Type
1942 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CB
Cade BE
LJ
Lee J
ST
Sofer T
WH
Wang H
ZM
Zhang M
CH
Chen H
GS
Gharib SA
GD
Gottlieb DJ
GX
Guo X
LJ
Lane JM
LJ
Liang J
LX
Lin X
MH
Mei H
PS
Patel SR
PS
Purcell SM
SR
Saxena R
SN
Shah NA
ED
Evans DS
HC
Hanis CL
HD
Hillman DR
MS
Mukherjee S
PL
Palmer LJ
SK
Stone KL
TG
Tranah GJ
AG
Abecasis GR
BE
Boerwinkle EA
CA
Correa A
CL
Cupples LA
KR
Kaplan RC
ND
Nickerson DA
NK
North KE
PB
Psaty BM
RJ
Rotter JI
RS
Rich SS
TR
Tracy RP
VR
Vasan RS
WJ
Wilson JG
ZX
Zhu X
RS
Redline S
Chapter II

Abstract

Summary of the research findings

Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered breathing remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) program, we performed the first whole-genome sequence analysis of sleep-disordered breathing.

1,942 African American individuals

Chapter III

Study Statistics

Key metrics and study information

1942
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, European, Hispanic or Latin American, East Asian
Ancestry
U.S., Australia
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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