Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians.
Xiu X, Zhang H, Xue A et al.
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Abstract
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Observational studies have revealed that type 2 diabetes (T2D) is associated with an increased risk of peripheral artery disease (PAD). However, whether the two diseases share a genetic basis and whether the relationship is causal remain unclear. It is also unclear as to whether these relationships differ between ethnic groups.
21,926 European ancestry type 2 diabetes cases, 5,673 European ancestry peripheral artery disease cases, 702,298 European ancestry controls
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