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A large-scale genome-wide association study on female genital tract polyps highlights role of DNA repair, cell proliferation, and cell growth.

Pathare ADS, Džigurski J, Pujol-Gualdo N et al.

39986329 PubMed ID
GWAS Study Type
457977 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PA
Pathare ADS
DJ
Džigurski J
PN
Pujol-Gualdo N
RV
Rukins V
PM
Peters M
MR
Mägi R
SA
Salumets A
SM
Saare M
LT
Laisk T
Chapter II

Abstract

Summary of the research findings

Study question: Can a large-scale genome-wide association study (GWAS) meta-analysis identify genomic risk loci and likely involved genes for female genital tract (FGT) polyps, provide insights into the biological mechanism underlying their development, and inform of potential overlap with other traits, including endometrial cancer?

36,984 European ancestry cases, 420,993 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

457977
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K., Estonia
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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