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Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe.

Raveane A, A Aneli, S S et al.

31517044 PubMed ID
72 Authors
2019-09-04 Published
6,403 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RA
Raveane A
AA
A Aneli
SS
S S
MF
Montinaro F
FA
F Athanasiadis
GG
G G
BS
Barlera S
SB
S Birolo
GG
G G
BG
Boncoraglio G
GD
G Di Blasio
AM
A M AM
DG
Di Gaetano C
CP
C Pagani
LL
L L
PS
Parolo S
SP
S Paschou
PP
P P
PA
Piazza A
AS
A Stamatoyannopoulos
GG
G G
AA
Angius A
AB
A Brucato
NN
N N
CF
Cucca F
FH
F Hellenthal
GG
G G
MA
Mulas A
AP
A Peyret-Guzzon
MM
M M
ZM
Zoledziewska M
MB
M Baali
AA
A A
BC
Bycroft C
CC
C Cherkaoui
MM
M M
CJ
Chiaroni J
JD
J Di Cristofaro
JJ
J J
DC
Dina C
CD
C Dugoujon
JM
J M JM
GP
Galan P
PG
P Giemza
JJ
J J
KT
Kivisild T
TM
T Mazieres
SS
S S
MM
Melhaoui M
MM
M Metspalu
MM
M M
MS
Myers S
SP
S Pereira
LL
L L
RF
Ricaut F X
FB
FX Brisighelli
FF
F F
CI
Cardinali I
IG
I Grugni
VV
V V
LH
Lancioni H
HP
H Pascali
VL
V L VL
TA
Torroni A
AS
A Semino
OO
O O
MG
Matullo G
GA
G Achilli
AA
A A
OA
Olivieri A
AC
A Capelli
CC
C C
Chapter II

Abstract

Summary of the research findings

European populations display low genetic differentiation as the result of long-term blending of their ancient founding ancestries. However, it is unclear how the combination of ancient ancestries related to early foragers, Neolithic farmers, and Bronze Age nomadic pastoralists can explain the distribution of genetic variation across Europe. Populations in natural crossroads like the Italian peninsula are expected to recapitulate the continental diversity, but have been systematically understudied. Here, we characterize the ancestry profiles of Italian populations using a genome-wide dataset representative of modern and ancient samples from across Italy, Europe, and the rest of the world. Italian genomes capture several ancient signatures, including a non-steppe contribution derived ultimately from the Caucasus. Differences in ancestry composition, as the result of migration and admixture, have generated in Italy the largest degree of population structure detected so far in the continent, as well as shaping the amount of Neanderthal DNA in modern-day populations.

Chapter III

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of ancestry and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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Historical Context