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GWAS Study

Risk alleles for multiple sclerosis identified by a genomewide study.

Hafler DA, Compston A, Sawcer S et al.

17660530 PubMed ID
GWAS Study Type
12360 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HD
Hafler DA
CA
Compston A
SS
Sawcer S
LE
Lander ES
DM
Daly MJ
DJ
De Jager PL
DB
de Bakker PI
GS
Gabriel SB
MD
Mirel DB
IA
Ivinson AJ
PM
Pericak-Vance MA
GS
Gregory SG
RJ
Rioux JD
MJ
McCauley JL
HJ
Haines JL
BL
Barcellos LF
CB
Cree B
OJ
Oksenberg JR
HS
Hauser SL
Chapter II

Abstract

Summary of the research findings

Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to identify alleles associated with the risk of multiple sclerosis.

931 European ancestry trios, 2,431 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

12360
Total Participants
GWAS
Study Type
Yes
Replicated
609 European ancestry trios, 2,322 European ancestry cases, 2,987 European ancestry controls
Replication Participants
European
Ancestry
U.S., U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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