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Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.

Ridker PM, Paré G, Parker AN et al.

20031564 PubMed ID
GWAS Study Type
18245 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RP
Ridker PM
PG
Paré G
PA
Parker AN
ZR
Zee RY
MJ
Miletich JP
CD
Chasman DI
Chapter II

Abstract

Summary of the research findings

Recent trial data have challenged the hypothesis that cholesteryl ester transfer protein (CETP) and high-density lipoprotein cholesterol (HDL-C) have causal roles in atherothrombosis. One method to evaluate this issue is to examine whether polymorphisms in the CETP gene that impact on HDL-C levels also impact on the future development of myocardial infarction.

18,245 European ancestry females

Chapter III

Study Statistics

Key metrics and study information

18245
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

AI-Generated Summary

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