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GWAS Study

Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.

Arking DE, Reinier K, Post W et al.

20360844 PubMed ID
GWAS Study Type
20261 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AD
Arking DE
RK
Reinier K
PW
Post W
JJ
Jui J
HG
Hilton G
OA
O'Connor A
PR
Prineas RJ
BE
Boerwinkle E
PB
Psaty BM
TG
Tomaselli GF
RT
Rea T
SN
Sotoodehnia N
SD
Siscovick DS
BG
Burke GL
ME
Marban E
SP
Spooner PM
CA
Chakravarti A
CS
Chugh SS
Chapter II

Abstract

Summary of the research findings

Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic determinants of SCA.

424 European ancestry cases, 226 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

20261
Total Participants
GWAS
Study Type
Yes
Replicated
521 cases and 19,090 controls of Black and European ancestry
Replication Participants
European, European, African unspecified
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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