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GWAS Study

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Patsopoulos NA, Esposito F, Reischl J et al.

22190364 PubMed ID
GWAS Study Type
17698 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PN
Patsopoulos NA
EF
Esposito F
RJ
Reischl J
LS
Lehr S
BD
Bauer D
HJ
Heubach J
SR
Sandbrink R
PC
Pohl C
EG
Edan G
KL
Kappos L
MD
Miller D
MJ
Montalbán J
PC
Polman CH
FM
Freedman MS
HH
Hartung HP
AB
Arnason BG
CG
Comi G
CS
Cook S
FM
Filippi M
GD
Goodin DS
JD
Jeffery D
OP
O'Connor P
EG
Ebers GC
LD
Langdon D
RA
Reder AT
TA
Traboulsee A
ZF
Zipp F
SS
Schimrigk S
HJ
Hillert J
BM
Bahlo M
BD
Booth DR
BS
Broadley S
BM
Brown MA
BB
Browning BL
BS
Browning SR
BH
Butzkueven H
CW
Carroll WM
CC
Chapman C
FS
Foote SJ
GL
Griffiths L
KA
Kermode AG
KT
Kilpatrick TJ
LJ
Lechner-Scott J
MM
Marriott M
MD
Mason D
MP
Moscato P
HR
Heard RN
PM
Pender MP
PV
Perreau VM
PD
Perera D
RJ
Rubio JP
SR
Scott RJ
SM
Slee M
SJ
Stankovich J
SG
Stewart GJ
TB
Taylor BV
TN
Tubridy N
WE
Willoughby E
WJ
Wiley J
MP
Matthews P
BF
Boneschi FM
CA
Compston A
HJ
Haines J
HS
Hauser SL
MJ
McCauley J
IA
Ivinson A
OJ
Oksenberg JR
PM
Pericak-Vance M
SS
Sawcer SJ
DJ
De Jager PL
HD
Hafler DA
DB
de Bakker PI
Chapter II

Abstract

Summary of the research findings

Objective: To perform a 1-stage meta-analysis of genome-wide association studies (GWAS) of multiple sclerosis (MS) susceptibility and to explore functional consequences of new susceptibility loci.

5,545 European ancestry cases, 12,153 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

17698
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., Australia, Netherlands, U.K., Switzerland, New Zealand
Recruitment Country
Chapter IV

AI-Generated Summary

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