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GWAS Study

A common variant near the KCNJ2 gene is associated with T-peak to T-end interval.

Marjamaa A, Oikarinen L, Porthan K et al.

22342860 PubMed ID
GWAS Study Type
5615 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MA
Marjamaa A
OL
Oikarinen L
PK
Porthan K
RS
Ripatti S
PG
Peloso G
NP
Noseworthy PA
VM
Viitasalo M
NM
Nieminen MS
TL
Toivonen L
KK
Kontula K
PL
Peltonen L
HA
Havulinna AS
JA
Jula A
OC
O'Donnell CJ
NC
Newton-Cheh C
PM
Perola M
SV
Salomaa V
Chapter II

Abstract

Summary of the research findings

T-peak to T-end (TPE) interval on the electrocardiogram is a measure of myocardial dispersion of repolarization and is associated with an increased risk of ventricular arrhythmias. The genetic factors affecting the TPE interval are largely unknown.

1,870 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

5615
Total Participants
GWAS
Study Type
Yes
Replicated
3,745 European ancestry individuals
Replication Participants
European
Ancestry
Finland, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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