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GWAS Study

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E et al.

23505323 PubMed ID
GWAS Study Type
4361 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WD
Weissglas-Volkov D
AC
Aguilar-Salinas CA
NE
Nikkola E
DK
Deere KA
CI
Cruz-Bautista I
AO
Arellano-Campos O
ML
Muñoz-Hernandez LL
GL
Gomez-Munguia L
OM
Ordoñez-Sánchez ML
RP
Reddy PM
LA
Lusis AJ
MN
Matikainen N
TM
Taskinen MR
RL
Riba L
CR
Cantor RM
SJ
Sinsheimer JS
TT
Tusie-Luna T
PP
Pajukanta P
Chapter II

Abstract

Summary of the research findings

The Mexican population and others with Amerindian heritage exhibit a substantial predisposition to dyslipidemias and coronary heart disease. Yet, these populations remain underinvestigated by genomic studies, and to date, no genome-wide association (GWA) studies have been reported for lipids in these rapidly expanding populations.

1,122 Mexican ancestry cases, 1,118 Mexican ancestry controls

Chapter III

Study Statistics

Key metrics and study information

4361
Total Participants
GWAS
Study Type
Yes
Replicated
1,067 Mexican ancestry cases, 1,054 Mexican ancestry controls
Replication Participants
Hispanic or Latin American
Ancestry
Mexico
Recruitment Country
Chapter IV

AI-Generated Summary

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