Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.
Feenstra B, Geller F, Carstensen L et al.
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Abstract
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Importance: Infantile hypertrophic pyloric stenosis (IHPS) is a serious condition in which hypertrophy of the pyloric sphincter muscle layer leads to gastric outlet obstruction. Infantile hypertrophic pyloric stenosis shows strong familial aggregation and heritability, but knowledge about specific genetic risk variants is limited.
1,001 European ancestry cases, 2,371 European ancestry controls
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