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Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery.

Karhausen JA, Qi W, Smeltz AM et al.

30103242 PubMed ID
GWAS Study Type
608 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KJ
Karhausen JA
QW
Qi W
SA
Smeltz AM
LY
Li YJ
SS
Shah SH
KW
Kraus WE
MJ
Mathew JP
PM
Podgoreanu MV
KM
Kertai MD
Chapter II

Abstract

Summary of the research findings

Introduction: Thrombocytopenia after cardiac surgery independently predicts stroke, acute kidney injury and death. To understand the underlying risks and mechanisms, we analysed genetic variations associated with thrombocytopenia in patients undergoing coronary artery bypass grafting (CABG) surgery.

176 European ancestry cases, 268 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

608
Total Participants
GWAS
Study Type
Yes
Replicated
76 European ancestry cases, 70 European ancestry cases
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

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AI-generated by DNAGENICS

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