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Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study.

Brouwer WP, Chan HLY, Lampertico P et al.

30715261 PubMed ID
GWAS Study Type
414 Participants
38 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BW
Brouwer WP
CH
Chan HLY
LP
Lampertico P
HJ
Hou J
TP
Tangkijvanich P
RH
Reesink HW
ZW
Zhang W
MA
Mangia A
TT
Tanwandee T
MG
Montalto G
SK
Simon K
ON
Ormeci N
CL
Chen L
TF
Tabak F
GF
Gunsar F
FR
Flisiak R
FP
Ferenci P
AM
Akdogan M
AF
Akyuz F
HN
Hirankarn N
JL
Jansen L
WV
Wong VW
SR
Soffredini R
LX
Liang X
CS
Chen S
GZ
Groothuismink ZMA
SR
Santoro R
JJ
Jaroszewicz J
OR
Ozaras R
KK
Kozbial K
BM
Brahmania M
XQ
Xie Q
CW
Chotiyaputta W
XQ
Xun Q
PM
Pazgan-Simon M
OE
Oztas E
VE
Verhey E
MN
Montanari NR
SJ
Sun J
HB
Hansen BE
BA
Boonstra A
JH
Janssen HLA
Chapter II

Abstract

Summary of the research findings

(Pegylated) Interferon ([Peg]IFN) therapy leads to response in a minority of chronic hepatitis B (CHB) patients. Host genetic determinants of response are therefore in demand.

161 Asian, European, African and other ancestry cases, 253 Asian, European, African and other ancestry controls

Chapter III

Study Statistics

Key metrics and study information

414
Total Participants
GWAS
Study Type
No
Replicated
European, African unspecified, Asian unspecified, NR
Ancestry
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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