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GWAS Study

Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche.

Sarnowski C, Cousminer DL, Franceschini N et al.

34021356 PubMed ID
GWAS Study Type
24176 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SC
Sarnowski C
CD
Cousminer DL
FN
Franceschini N
RL
Raffield LM
JG
Jia G
FL
Fernández-Rhodes L
GS
Grant SFA
HH
Hakonarson H
LL
Lange LA
LJ
Long J
ST
Sofer T
TR
Tao R
WR
Wallace RB
WQ
Wong Q
ZG
Zirpoli G
BE
Boerwinkle E
BJ
Bradfield JP
CA
Correa A
KC
Kooperberg CL
NK
North KE
PJ
Palmer JR
ZB
Zemel BS
ZW
Zheng W
MJ
Murabito JM
LK
Lunetta KL
Chapter II

Abstract

Summary of the research findings

Study question: Does the expansion of genome-wide association studies (GWAS) to a broader range of ancestries improve the ability to identify and generalise variants associated with age at menarche (AAM) in European populations to a wider range of world populations?

19,028 African ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

24176
Total Participants
GWAS
Study Type
Yes
Replicated
5,148 African ancestry individuals
Replication Participants
African American or Afro-Caribbean, African unspecified, African unspecified, Hispanic or Latin American, East Asian, South Asian
Ancestry
U.K., U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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