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GWAS Study

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.

McCartney DL, Min JL, Richmond RC et al.

34187551 PubMed ID
GWAS Study Type
34470 Participants
136 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MD
McCartney DL
MJ
Min JL
RR
Richmond RC
LA
Lu AT
SM
Sobczyk MK
DG
Davies G
BL
Broer L
GX
Guo X
JA
Jeong A
JJ
Jung J
KS
Kasela S
KS
Katrinli S
KP
Kuo PL
MP
Matias-Garcia PR
MP
Mishra PP
NM
Nygaard M
PT
Palviainen T
PA
Patki A
RL
Raffield LM
RS
Ratliff SM
RT
Richardson TG
RO
Robinson O
SM
Soerensen M
SD
Sun D
TP
Tsai PC
VD
van der Zee MD
WR
Walker RM
WX
Wang X
WY
Wang Y
XR
Xia R
XZ
Xu Z
YJ
Yao J
ZW
Zhao W
CA
Correa A
BE
Boerwinkle E
DP
Dugué PA
DP
Durda P
EH
Elliott HR
GC
Gieger C
DG
de Geus EJC
HS
Harris SE
HG
Hemani G
IM
Imboden M
KM
Kähönen M
KS
Kardia SLR
KJ
Kresovich JK
LS
Li S
LK
Lunetta KL
MM
Mangino M
MD
Mason D
MA
McIntosh AM
MJ
Mengel-From J
MA
Moore AZ
MJ
Murabito JM
OM
Ollikainen M
PJ
Pankow JS
PN
Pedersen NL
PA
Peters A
PS
Polidoro S
PD
Porteous DJ
RO
Raitakari O
RS
Rich SS
SD
Sandler DP
SE
Sillanpää E
SA
Smith AK
SM
Southey MC
SK
Strauch K
TH
Tiwari H
TT
Tanaka T
TT
Tillin T
UA
Uitterlinden AG
VD
Van Den Berg DJ
VD
van Dongen J
WJ
Wilson JG
WJ
Wright J
YI
Yet I
AD
Arnett D
BS
Bandinelli S
BJ
Bell JT
BA
Binder AM
BD
Boomsma DI
CW
Chen W
CK
Christensen K
CK
Conneely KN
EP
Elliott P
FL
Ferrucci L
FM
Fornage M
HS
Hägg S
HC
Hayward C
IM
Irvin M
KJ
Kaprio J
LD
Lawlor DA
LT
Lehtimäki T
LF
Lohoff FW
ML
Milani L
MR
Milne RL
PN
Probst-Hensch N
RA
Reiner AP
RB
Ritz B
RJ
Rotter JI
SJ
Smith JA
TJ
Taylor JA
VM
van Meurs JBJ
VP
Vineis P
WM
Waldenberger M
DI
Deary IJ
RC
Relton CL
HS
Horvath S
MR
Marioni RE
Chapter II

Abstract

Summary of the research findings

Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field.

34,470 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

34470
Total Participants
GWAS
Study Type
No
Replicated
European, African American or Afro-Caribbean
Ancestry
Denmark, Estonia, Finland, Germany, Italy, Netherlands, Sweden, Switzerland, U.K., U.S., Australia
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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