Bidirectional relationship between type 2 diabetes mellitus and coronary artery disease: Prospective cohort study and genetic analyses.
Zhang W, Zhang L, Xiao C et al.
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Abstract
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While type 2 diabetes mellitus (T2DM) is considered a putative causal risk factor for coronary artery disease (CAD), the intrinsic link underlying T2DM and CAD is not fully understood. We aimed to highlight the importance of integrated care targeting both diseases by investigating the phenotypic and genetic relationships between T2DM and CAD.
74,124 European ancestry type 2 diabetes cases, 181,522 European ancestry coronary artery disease cases, 1,808,174 European ancestry controls
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