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GWAS Study

Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals.

Lee JH, Cheng R, Barral S et al.

21059989 PubMed ID
GWAS Study Type
5118 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LJ
Lee JH
CR
Cheng R
BS
Barral S
RC
Reitz C
MM
Medrano M
LR
Lantigua R
JI
Jiménez-Velazquez IZ
RE
Rogaeva E
SG
St George-Hyslop PH
MR
Mayeux R
Chapter II

Abstract

Summary of the research findings

Objectives: To identify novel loci for late-onset Alzheimer disease (LOAD) in Caribbean Hispanic individuals and to replicate the findings in a publicly available data set from the National Institute on Aging Late-Onset Alzheimer's Disease Family Study.

549 Caribbean Hispanic cases, 544 Caribbean Hispanic controls

Chapter III

Study Statistics

Key metrics and study information

5118
Total Participants
GWAS
Study Type
Yes
Replicated
3,839 European ancestry individuals, 116 Caribbean Hispanic cases, 70 Caribbean Hispanic controls
Replication Participants
Hispanic or Latin American, African American or Afro-Caribbean, Other, European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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