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GWAS Study

Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.

Traglia M, Girelli D, Biino G et al.

21785125 PubMed ID
GWAS Study Type
1657 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Traglia M
GD
Girelli D
BG
Biino G
CN
Campostrini N
CM
Corbella M
SC
Sala C
MC
Masciullo C
VF
Viganò F
BI
Buetti I
PG
Pistis G
CM
Cocca M
CC
Camaschella C
TD
Toniolo D
Chapter II

Abstract

Summary of the research findings

Hepcidin is the main regulator of iron homeostasis: inappropriate production of hepcidin results in iron overload or iron deficiency and anaemia.

1,657 Val Borbera (founder/genetic isolate) individuals

Chapter III

Study Statistics

Key metrics and study information

1657
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Italy
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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